Specific arrests of spermatogenesis in genetically modified and mutant mice.

DG De Rooij, P De Boer - Cytogenetic & Genome Research, 2003 - karger.com
In naturally occurring mutant mice but also in mice genetically modified for the study of other
organs, relatively often a spermatogenic arrest is seen. In a number of cases the arrests …

Targeted Expression of Bcl-2 in Mouse Oocytes Inhibits Ovarian Follicle Atresia and Prevents Spontaneous and Chemotherapy-Induced Oocyte Apoptosis In Vitro

Y Morita, GI Perez, DV Maravei, KI Tilly… - Molecular …, 1999 - academic.oup.com
Members of the Bcl-2 family serve as central checkpoints for cell death regulation, and
overexpression of Bcl-2 is known to inhibit apoptosis in many cell types. To determine …

bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death

LH Boise, M González-García, CE Postema, L Ding… - cell, 1993 - cell.com
We report the isolation of b&x, a b&2-related gene that can function as a bcl-24ndependent
regulator of programed ceil death (apoptosis). Alternative splicing results in two distinct b&x …

Apoptosis and apoptosis-related proteins in human endometrium

TE Vaskivuo, F Stenbäck, P Karhumaa, J Risteli… - Molecular and cellular …, 2000 - Elsevier
Apoptosis has been shown to be an important regulator of endometrium function. To study
the regulation of apoptosis in the endometrium during the normal menstrual cycle, the …

Expression of bcl-2 and the progression of human and rodent prostatic cancers.

Y Furuya, S Krajewski, JI Epstein, JC Reed… - Clinical cancer research …, 1996 - AACR
The frequency of bcl-2 protein expression was evaluated using immunocytochemical
staining during the progression of human and rat prostate cancer from an androgen …

Mouse vaginal opening is an apoptosis-dependent process which can be prevented by the overexpression of Bcl2

I Rodriguez, K Araki, K Khatib, JC Martinou… - Developmental …, 1997 - Elsevier
In the mouse, opening of the vaginal cavity to the skin is a late event, occurring around the
fifth week of life; it can be induced in sexually immature mice by β-estradiol injections. We …

[PDF][PDF] The role of BH3-only proteins in apoptosis within the ovary

KJ Hutt - Reproduction, 2015 - scholar.archive.org
REPRODUCTION Page 1 REPRODUCTION REVIEW The role of BH3-only proteins in apoptosis
within the ovary Karla J Hutt1,2 1MIMR-PHI, Clayton, Victoria, Australia and 2Department of …

Overexpression of bcl-2 Protects Prostate Cancer Cells from Apoptosis in Vitro and Confers Resistance to Androgen Depletion in Vivo

AJ Raffo, H Perlman, MW Chen, ML Day, JS Streitman… - Cancer research, 1995 - AACR
Normal (nonneoplastic) human prostatic secretory epithelial cells do not express the bcl-2
protein. However, a recent immunohistochemical survey of neoplastic human prostate …

Expression of Bcl-2 and Bax in the human corpus luteum during the menstrual cycle and in early pregnancy: regulation by human chorionic gonadotropin

N Sugino, T Suzuki, S Kashida, A Karube… - The Journal of …, 2000 - academic.oup.com
To investigate the relationship between apoptosis and the Bcl-2/Bax system in the human
corpus luteum (CL), the frequency of apoptosis and expression of Bcl-2 and Bax were …

[HTML][HTML] Bcl-2 and Bax mammalian regulators of apoptosis are functional in Drosophila

S Gaumer, I Guénal, S Brun, L Théodore… - Cell Death & …, 2000 - nature.com
Studies of apoptosis in C. elegans have allowed the identification of three genes, ced-3, ced-
4 and ced-9. Their products constitute the components of an induction pathway of apoptosis …