Solutions of table salt (NaCl) elicit several tastes, including of course saltiness but also
sweet, sour, and bitter. This brief review touches on some of the mileposts concerning what …

Mammals perceive the five different taste qualities: bitter, sweet, umami, sour, and salty. At
least two different mechanisms contribute to salt taste in rodents. One is elicited by various …

Our ability to detect salt (NaCl) in food and beverages (salt taste) depends on the activity of
taste cells, biological sensors localized in the oral cavity. Salt taste is mainly due to sodium …

Taste reception is fundamental for the proper selection of food and beverages. Among the
several chemicals recognized by the human taste system, sodium ions (Na+) are of …

Biophysical studies of isolated taste receptor cells show that one transduction mechanism
for Na+ salts involves the inward movement of Na+ through an apical ion channel, which is …

Recent research on cellular mechanisms of peripheral taste has defined transduction
pathways involving membrane receptors, G proteins, second messengers, and ion …

Publisher Summary The concept that salt taste is mediated by amiloride-blockable sodium
ion (Na+) channels located in the apical membranes of taste cells is interesting. The original …

How taste buds detect NaCl remains poorly understood. Among other problems, applying
taste-relevant concentrations of NaCl (50–500 mm) onto isolated taste buds or cells exposes …

It is well established from psychophysical and electrophysiological measurements that both
Na and Cl contribute to the taste response to NaCl. The contribution of Na to the NaCl …

Taste receptor cells, which detect sapid molecules, are grouped in taste buds within the
lingual and other epithelia of the oral cavity. Their apical poles are morphologically …