Cognitive impairments in humans and animals have been linked to dysfunction of neurons
in the basal forebrain cholinergic system (BFCS). Degeneration of these cells may be, in …

The cholinergic hypothesis of memory dysfunctionof cholionergic neurons in the basal
forebrain cholinergic system (BFCS) may be responsible for the memory deficits associated …

THE role of the basal forebrain cholinergic system in learning and memory has held
considerable interest since the discovery of cholinergic neurodegeneration in the basal …

Ibotenic acid and kainic acid lesions of the basal forebrain induce profound deficits in
performance on a wide variety of tasks involving discrimination learning and memory. These …

Within the basal forebrain is a population of magnocellular neurons that provides cholinergic
innervation to the hippocampus, olfactory bulb, amygdala and cortex. Extensive lesion and …

Recent neuropsychological studies suggest that, in addition to prominent mnemonic
dysfunction, attentional impairments are a core feature of Alzheimer disease (AD). As is the …

The nucleus basalis of Meynert provides diffuse cholinergic input to the neocortex. When
compared with an age‐and sex‐matched control, the nucleus basalis from a patient with …

A substantial body of literature has suggested that the memory and learning deficits
associated with Alzheimer's disease are attributable to degeneration of the cholinergic …

Rats were trained for several months to perform a radial arm maze task and then given
either sham or ibotenic acid lesions of the nucleus basalis magnocellularis (NBM), the …

The cholinergic basal forebrain (CBF) degenerates in Alzheimer's Disease (AD), and the
degree of this degeneration correlates with the degree of dementia. In the present study we …