Basal forebrain lesions in monkeys disrupt attention but not learning and memory [published erratum appears in J Neurosci 1995 Mar; 15 (3): following table of …
ML Voytko, DS Olton, RT Richardson… - Journal of …, 1994 - Soc Neuroscience
Cognitive impairments in humans and animals have been linked to dysfunction of neurons
in the basal forebrain cholinergic system (BFCS). Degeneration of these cells may be, in …
in the basal forebrain cholinergic system (BFCS). Degeneration of these cells may be, in …
Cognitive functions of the basal forebrain cholinergic system in monkeys: memory or attention?
ML Voytko - Behavioural brain research, 1996 - Elsevier
The cholinergic hypothesis of memory dysfunctionof cholionergic neurons in the basal
forebrain cholinergic system (BFCS) may be responsible for the memory deficits associated …
forebrain cholinergic system (BFCS) may be responsible for the memory deficits associated …
Intact spatial learning following lesions of basal forebrain cholinergic neurons
THE role of the basal forebrain cholinergic system in learning and memory has held
considerable interest since the discovery of cholinergic neurodegeneration in the basal …
considerable interest since the discovery of cholinergic neurodegeneration in the basal …
The basal forebrain-cortical cholinergic system: interpreting the functional consequences of excitotoxic lesions
SB Dunnett, BJ Everitt, TW Robbins - Trends in neurosciences, 1991 - cell.com
Ibotenic acid and kainic acid lesions of the basal forebrain induce profound deficits in
performance on a wide variety of tasks involving discrimination learning and memory. These …
performance on a wide variety of tasks involving discrimination learning and memory. These …
Choline-induced spatial memory facilitation correlates with altered distribution and morphology of septal neurons
R Loy, D Heyer, CL Williams, WH Meck - The basal forebrain: Anatomy to …, 1991 - Springer
Within the basal forebrain is a population of magnocellular neurons that provides cholinergic
innervation to the hippocampus, olfactory bulb, amygdala and cortex. Extensive lesion and …
innervation to the hippocampus, olfactory bulb, amygdala and cortex. Extensive lesion and …
Alzheimer disease, attention, and the cholinergic system
AD Lawrence, BJ Sahakian - Alzheimer Disease & Associated …, 1995 - journals.lww.com
Recent neuropsychological studies suggest that, in addition to prominent mnemonic
dysfunction, attentional impairments are a core feature of Alzheimer disease (AD). As is the …
dysfunction, attentional impairments are a core feature of Alzheimer disease (AD). As is the …
Alzheimer disease: evidence for selective loss of cholinergic neurons in the nucleus basalis
PJ Whitehouse, DL Price, AW Clark… - Annals of Neurology …, 1981 - Wiley Online Library
The nucleus basalis of Meynert provides diffuse cholinergic input to the neocortex. When
compared with an age‐and sex‐matched control, the nucleus basalis from a patient with …
compared with an age‐and sex‐matched control, the nucleus basalis from a patient with …
Excitotoxic lesions of basal forebrain cholinergic neurons: effects on learning, memory and attention
JL Muir, KJ Page, DJS Sirinathsinghji… - Behavioural brain …, 1993 - Elsevier
A substantial body of literature has suggested that the memory and learning deficits
associated with Alzheimer's disease are attributable to degeneration of the cholinergic …
associated with Alzheimer's disease are attributable to degeneration of the cholinergic …
Selective memory loss following nucleus basalis lesions: long term behavioral recovery despite persistent cholinergic deficiencies
RT Bartus, C Flicker, RL Dean, M Pontecorvo… - Pharmacology …, 1985 - Elsevier
Rats were trained for several months to perform a radial arm maze task and then given
either sham or ibotenic acid lesions of the nucleus basalis magnocellularis (NBM), the …
either sham or ibotenic acid lesions of the nucleus basalis magnocellularis (NBM), the …
Threshold relationship between lesion extent of the cholinergic basal forebrain in the rat and working memory impairment in the radial maze
CC Wrenn, DA Lappi, RG Wiley - Brain research, 1999 - Elsevier
The cholinergic basal forebrain (CBF) degenerates in Alzheimer's Disease (AD), and the
degree of this degeneration correlates with the degree of dementia. In the present study we …
degree of this degeneration correlates with the degree of dementia. In the present study we …