Synthesis and Characterization of Palmitoyl-block-poly(methacryloyloxyethyl phosphorylcholine) Polymer Micelles for Anticancer Drug Delivery
We report the synthesis and characterization of an amphiphilic polymer comprising a
hydrophobic palmitoyl (Pal) group and a zwitterionic poly (2-methacryloyloxyethyl …
hydrophobic palmitoyl (Pal) group and a zwitterionic poly (2-methacryloyloxyethyl …
In vitro and in vivo anti-tumor efficiency comparison of phosphorylcholine micelles with PEG micelles
M Cai, J Cao, Z Wu, F Cheng, Y Chen, X Luo - Colloids and Surfaces B …, 2017 - Elsevier
Polymer micelles for anticancer drug delivery have shown many advantages. In this study,
poly (ε-caprolactone)-b-poly (2-methacryloyloxyethyl phosphorylcholine)(PCL-PMPC) with …
poly (ε-caprolactone)-b-poly (2-methacryloyloxyethyl phosphorylcholine)(PCL-PMPC) with …
Enhancement of cellular uptake and antitumor efficiencies of micelles with phosphorylcholine
S Tu, YW Chen, YB Qiu, K Zhu… - Macromolecular …, 2011 - Wiley Online Library
Internalization of drug delivery micelles into cancer cells is a crucial step for antitumor
therapeutics. Novel amphiphilic star‐shaped copolymers with zwitterionic phosphorylcholine …
therapeutics. Novel amphiphilic star‐shaped copolymers with zwitterionic phosphorylcholine …
Biocompatible Poly(D,L‐lactide)‐block‐Poly(2‐methacryloyloxyethylphosphorylcholine) Micelles for Drug Delivery
Well‐defined amphiphilic PLA‐b‐PMPC diblock copolymers were synthesized. Bimimetic
micelles were prepared and applied for release of anti‐cancer drugs (DOX). TEM and DLS …
micelles were prepared and applied for release of anti‐cancer drugs (DOX). TEM and DLS …
Effects of copolymer component on the properties of phosphorylcholine micelles
Z Wu, M Cai, J Cao, J Zhang, X Luo - International Journal of …, 2017 - Taylor & Francis
Zwitterionic polymers have unique features, such as good compatibility, and show promise
in the application of drug delivery. In this study, the zwitterionic copolymers, poly (ε …
in the application of drug delivery. In this study, the zwitterionic copolymers, poly (ε …
A pH‐Sensitive Phospholipid Polymeric Prodrug Based on Branched Polyethylenimine for Intracellular Drug Delivery
H Wang, J Xiong, G Liu, Y Wang - … Chemistry and Physics, 2016 - Wiley Online Library
A biomimic pH‐sensitive polymeric prodrug based on branched polyethylenimine‐graft‐12‐
acryloyloxy dodecyl phosphorylcholine and 6‐maleimidocaproyl‐doxorubicin is rationally …
acryloyloxy dodecyl phosphorylcholine and 6‐maleimidocaproyl‐doxorubicin is rationally …
Cellular uptake of pH/reduction responsive phosphorylcholine micelles
Y Cai, S Li, M Cai, Y Chen, X Luo - New Journal of Chemistry, 2017 - pubs.rsc.org
Phosphorylcholine micelles based on pH/reduction responsive copolymers, poly (ε-
caprolactone)-ss-b-poly ((N, N-diethylaminoethyl methacrylate)-r-poly (2 …
caprolactone)-ss-b-poly ((N, N-diethylaminoethyl methacrylate)-r-poly (2 …
Drug carrier system self-assembled from biomimetic polyphosphorycholine and biodegradable polypeptide based diblock copolymers
Polymeric nanoscale drug carrier systems are of particular interest for tumor therapy, offering
significant advantages of improved targeting and efficacy. Herein, a well-defined polymeric …
significant advantages of improved targeting and efficacy. Herein, a well-defined polymeric …
Novel biomimetic polymersomes as polymer therapeutics for drug delivery
JP Xu, J Ji, WD Chen, JC Shen - Journal of controlled release, 2005 - Elsevier
Novel amphiphilic diblock copolymers, cholesterol-end-capped poly (2-methacryloyloxyethyl
phosphorylcholine)(CMPC), which have poly (2-methacryloyloxyethyl phosphorylcholine) …
phosphorylcholine)(CMPC), which have poly (2-methacryloyloxyethyl phosphorylcholine) …
Tracing difference: in vitro and in vivo antitumor property comparison of pH-sensitive biomimetic phosphorylcholine micelles with insensitive micelles
Q Wang, D Lei, F Chen, Y Chen… - ACS Biomaterials Science …, 2019 - ACS Publications
Although smart polymer micelles able to respond to the tumor acid microenvironment are
potential anticancer drug carriers, fruitful clinical application of these carriers is inadequate …
potential anticancer drug carriers, fruitful clinical application of these carriers is inadequate …