[HTML][HTML] PM2.5-induced oxidative stress increases intercellular adhesion molecule-1 expression in lung epithelial cells through the IL-6/AKT/STAT3/NF-κB-dependent …

CW Liu, TL Lee, YC Chen, CJ Liang, SH Wang… - Particle and fibre …, 2018 - Springer
Background Epidemiological studies have shown that ambient air pollution is closely
associated with increased respiratory inflammation and decreased lung function. Particulate …

PM2. 5‐induced lung inflammation in mice: Differences of inflammatory response in macrophages and type II alveolar cells

M He, T Ichinose, S Yoshida, T Ito, C He… - Journal of Applied …, 2017 - Wiley Online Library
Abstract Particulate matter 2.5 (< PM2. 5 μm) leads to chronic obstructive pulmonary
disease. In this study, biomarkers related to inflammation and oxidative stress in vitro and in …

Water‐insoluble fraction of airborne particulate matter (PM10) induces oxidative stress in human lung epithelial A549 cells

S Yi, F Zhang, F Qu, W Ding - Environmental toxicology, 2014 - Wiley Online Library
Exposure to ambient airborne particulate matter (PM) with an aerodynamic diameter less
than 10 μm (PM10) links with public health hazards and increases risk for lung cancer and …

PM2.5‐induced oxidative stress increases adhesion molecules expression in human endothelial cells through the ERK/AKT/NF‐κB‐dependent pathway

W Rui, L Guan, F Zhang, W Zhang… - Journal of Applied …, 2016 - Wiley Online Library
The aim of this study was to explore the intracellular mechanisms underlying the
cardiovascular toxicity of air particulate matter (PM) with an aerodynamic diameter of less …

Pro‐inflammatory response and oxidative stress induced by specific components in ambient particulate matter in human bronchial epithelial cells

L Yang, G Liu, Z Lin, Y Wang, H He, T Liu… - Environmental …, 2016 - Wiley Online Library
Previous studies have shown that biological effect of particulate matter (PM2. 5) is involved
in including chemical composition and mass concentration, but the precise components and …

PM2. 5 collected in China causes inflammatory and oxidative stress responses in macrophages through the multiple pathways

K Bekki, T Ito, Y Yoshida, C He, K Arashidani… - Environmental …, 2016 - Elsevier
Air pollution continues to increase in East Asia, particularly in China, and is considered to
cause serious health problems. In this study, we investigated the toxicological properties of …

Exposure to air pollution exacerbates inflammation in rats with preexisting COPD

J Wang, Y Li, P Zhao, Y Tian, X Liu, H He… - Mediators of …, 2020 - Wiley Online Library
Particulate matter with an aerodynamic diameter equal or less than 2.5 micrometers (PM2.
5) is associated with the development of chronic obstructive pulmonary disease (COPD) …

Ambient fine particulate matter (PM2. 5) induces oxidative stress and pro-inflammatory response via up-regulating the expression of CYP1A1/1B1 in human bronchial …

Q Yuan, Y Chen, X Li, Z Zhang, H Chu - Mutation Research/Genetic …, 2019 - Elsevier
We investigated the mechanism responsible for the oxidative stress and pro-inflammatory
response triggered by PM 2.5 collected from Nanjing of China. Two human bronchial …

Ambient particulate matter induces interleukin-8 expression through an alternative NF-κB (nuclear factor-kappa B) mechanism in human airway epithelial cells

R Silbajoris, AR Osornio-Vargas… - Environmental …, 2011 - ehp.niehs.nih.gov
Background: Exposure to ambient air particulate matter (PM) has been shown to increase
rates of cardiopulmonary morbidity and mortality, but the underlying mechanisms are still not …

PM2.5 Exposure Induces Inflammatory Response in Macrophages via the TLR4/COX-2/NF-κB Pathway

H Fu, X Liu, W Li, Y Zu, F Zhou, Q Shou, Z Ding - Inflammation, 2020 - Springer
Fine particulate matter with an aerodynamic diameter less than 2.5 μm (PM2. 5) is a serious
air pollutant associated with health problems. Macrophages play an important role in the …