Background: Early identification and prevention of hypoxic-ischemic encephalopathy (HIE)
in newborns may reduce neonatal mortality and neurological dysfunction. Objective: To …

Neuroprotective interventions in neonatal hypoxic-ischemic encephalopathy (HIE) require
early indicators of brain damage to initiate therapy. In order to find a reliable, rapid, and …

Hypoxic-ischemic encephalopathy (HIE) after perinatal asphyxia is a condition in which
serum concentrations of brain-specific biochemical markers may be elevated …

Neonatal hypoxic ischemic encephalopathy (HIE) is a common disease caused by perinatal
asphyxia, a major cause of neonatal death, neurological behavior, and long-term disability …

Abstract Early assessment of the severity of an acute cerebral lesion secondary to hypoxia-
ischemia or other pathologic conditions may provide a very useful basis for preventive or …

The initial diagnosis of neonatal hypoxic-ischemic encephalopathy is based on nervous
system clinical manifestations. The use of biomarkers to monitor brain injury and evaluate …

Background Neonatal hypoxic ischemic encephalopathy (HIE) is a devastating condition
resulting from a sustained lack of oxygen during birth. The interest in identifying a relevant …

Urinary S100B protein measurements: A tool for the early ide... : Critical Care Medicine Urinary
S100B protein measurements: A tool for the early identification of hypoxic-ischemic …

Objectives The early detection and stratification of asphyxiated infants at higher risk for
impaired neurodevelopment is challenging. S100B protein is a well-established biomarker …

Background Current diagnostic criteria for hypoxic–ischemic encephalopathy in the early
hours lack objective measurement tools. Therefore, this systematic review aims to identify …