Baicalin Represses Type Three Secretion System of Pseudomonas aeruginosa through PQS System
P Zhang, Q Guo, Z Wei, Q Yang, Z Guo, L Shen… - Molecules, 2021 - mdpi.com
Therapeutics that target the virulence of pathogens rather than their viability offer a
promising alternative for treating infectious diseases and circumventing antibiotic resistance …
promising alternative for treating infectious diseases and circumventing antibiotic resistance …
Baicalin inhibits biofilm formation, attenuates the quorum sensing-controlled virulence and enhances Pseudomonas aeruginosa clearance in a mouse peritoneal …
J Luo, B Dong, K Wang, S Cai, T Liu, X Cheng, D Lei… - PloS one, 2017 - journals.plos.org
The quorum sensing (QS) circuit plays a role in the precise regulation of genes controlling
virulence factors and biofilm formation in Pseudomonas aeruginosa. QS-controlled biofilm …
virulence factors and biofilm formation in Pseudomonas aeruginosa. QS-controlled biofilm …
Attenuation of quorum sensing controlled virulence factors and biofilm formation in Pseudomonas aeruginosa by pentacyclic triterpenes, betulin and betulinic acid
The production of virulence determinants and biofilm formation in numerous pathogens is
regulated by the cell-density-dependent phenomenon, Quorum sensing (QS). The QS …
regulated by the cell-density-dependent phenomenon, Quorum sensing (QS). The QS …
Baicalein attenuates the quorum sensing-controlled virulence factors of Pseudomonas aeruginosa and relieves the inflammatory response in P. aeruginosa-infected …
J Luo, J Kong, B Dong, H Huang, K Wang… - Drug design …, 2016 - Taylor & Francis
Burgeoning antibiotic resistance and unfavorable outcomes of inflammatory injury after
Pseudomonas aeruginosa infection have necessitated the development of novel agents that …
Pseudomonas aeruginosa infection have necessitated the development of novel agents that …
Derivatives of plant phenolic compound affect the type III secretion system of Pseudomonas aeruginosa via a GacS-GacA two-component signal transduction system
A Yamazaki, J Li, Q Zeng, D Khokhani… - Antimicrobial agents …, 2012 - Am Soc Microbiol
Antibiotic therapy is the most commonly used strategy to control pathogenic infections;
however, it has contributed to the generation of antibiotic-resistant bacteria. To circumvent …
however, it has contributed to the generation of antibiotic-resistant bacteria. To circumvent …
The Effects of Chinese Herbal Medicines on the Quorum Sensing-Regulated Virulence in Pseudomonas aeruginosa PAO1
The quorum sensing (QS) system has been used by many opportunistic pathogenic bacteria
to coordinate their virulence determinants in relation to cell-population density. As antibiotic …
to coordinate their virulence determinants in relation to cell-population density. As antibiotic …
[HTML][HTML] Baicalin ameliorates multidrug-resistant Pseudomonas aeruginosa induced pulmonary inflammation in rat via arginine biosynthesis
L Li, H Cui, Y Zhang, W Xie, Y Lin, Y Guo… - Biomedicine & …, 2023 - Elsevier
Multidrug-resistance (MDR) Pseudomonas aeruginosa (P. aeruginosa) is a lethal gram-
negative pathogen causing hospital-acquired and ventilator-associated pneumonia, which …
negative pathogen causing hospital-acquired and ventilator-associated pneumonia, which …
New insights into the antibacterial and quorum sensing inhibition mechanism of Artemisia argyi leaf extracts towards Pseudomonas aeruginosa PAO1
J Kong, Y Wang, K Xia, N Zang, H Zhang, X Liang - 3 Biotech, 2021 - Springer
This study aimed to investigate the anti-quorum sensing (QS) activity of Artemisia argyi leaf
extracts (AALE) towards Pseudomonas aeruginosa PAO1 as well as the underlying …
extracts (AALE) towards Pseudomonas aeruginosa PAO1 as well as the underlying …
Calpurnia aurea (Aiton) Benth Extracts Reduce Quorum Sensing Controlled Virulence Factors in Pseudomonas aeruginosa
Pseudomonas aeruginosa is the causative agent of several life-threatening human
infections. Like many other pathogens, P. aeruginosa exhibits quorum sensing (QS) …
infections. Like many other pathogens, P. aeruginosa exhibits quorum sensing (QS) …
Cranberry-derived proanthocyanidins impair virulence and inhibit quorum sensing of Pseudomonas aeruginosa
Bacteria have evolved multiple strategies for causing infections that include producing
virulence factors, undertaking motility, developing biofilms and invading host cells. N …
virulence factors, undertaking motility, developing biofilms and invading host cells. N …