gave after distillation 8 as a colorless oil [79%, bp 98-100 (0.07 mm)]: ir (neat) 2.80 (m) and
5.75 ĩ (s); 4H NMR 1.30 (3 H, trip-let, J= 7.0 Hz), 1.33 (3 H, triplet, J= 7.0 Hz), 1.57-2.55 (6 H …

1 large-scale preparation. As part of a research project1 23 directed toward an improved
synthesis of strigol and a wide range of analogues, we wished to devise a short and …

7, 7-Dimethyl-l, 4-dioxo-2, 3, 4, 5, 6, 7-hexahydroinden-2-yl-acetic acid'-3 (la, thereafter
shortly referred to as hydrindanacetic acid) is an important intermediate in various syntheses …

Experimental10 l-(5-Ethyl-2-pyridylmethyl)-2-indanol (XIII).—To an ethereal solution of
phenyllithium, 11 prepared from 6.1 g.(0.88 g.-atom) of lithium and 69 g.(0.44 mole) of …

The starting material, 4-methylindan-l-one, s was prepared from po-tolylpropionic acid by an
improvement of Bachmann's pr~ cedure.~ Treatment of the indanone with acrylonitrile in the …

In a related study of the reaction of Me2CuLi with the aryl cyclopropyl ketones 6-8 (all of
which have reduction potentials in the range—1.8 to—2.1 V vs. SCE), 3 the major product …

A total synthesis of (i)-warburganal has been completed starting from (i)—isodrimenin and
other drimane—type compounds. 11, 12—Diacetoxy-drim-8-ene (9), which can be readily …

4 is described in this paper. At the same time, we initi-ated studies directed toward
thesynthesis of a diacid analogous to la except that the 8-methyl group is re-placed by a 7 …

Y=; Z= OMe b, X= OMe; Y= Z= H in practice, basic reactionsof-unsubstituted cyclo-
pentanones produce high yields of aldol self-conden-sation products, 6 so that another route …

(8) Cf. H. Fritz, E. Besch, and T. Wieland, Ann., 668, 150 (1963). aluminum hydride reduction
of the dihydro product (3b), 11 and mild saponification of the diacyl derivative (3c) produced …