Renal injury is reported to have a high mortality rate. Additionally, there are several
limitations to current conventional treatments that are used to manage it. This study …

Objective Hesperidin is a well-known flavanone glycoside copiously found in sweet orange
and lemon, which was recently reported to possess significant anti-inflammatory, analgesic …

OBJECTIVE: As an antioxidant and anti-inflammatory agent, Hesperidin was investigated to
prove whether it prevents damage to the kidney and lung tissues of rats undergoing renal …

The present study investigated the probable protective effect of hesperidin against kidney
injury induced by methotrexate in rats. The rats received a single injection of methotrexate …

Renal ischemia-reperfusion injury (IRI) is a major cause of acute kidney injury (AKI). Our
previous studies have shown that the total flavonoids (TFs) from Rosa laevigata Michx fruit …

Background Renal ischemia–reperfusion (I/R) injury is a major cause of acute kidney failure
by mechanisms that involve oxidative stress, inflammation, and apoptosis. Penehyclidine …

The defensive effects of hesperidin (HDN, a bioflavonoid) was investigated on gentamicin
(GEN) provoked nephrotoxicity in rats. The expression patterns of nuclear factor (erythroid …

The kidney plays a central role in detoxification and excretion of toxic metabolites, and
therefore is susceptible to toxicity by xenobiotics. Hesperidin is a citrus flavonoid with …

In the present study, the protective effect and the potential underlying mechanism of
rutaecarpine (Ru) on renal ischemia reperfusion injury (IRI) in rats were investigated. A renal …

Background Renal ischemia/reperfusion (I/R)-induced acute kidney injury remains to be a
troublesome condition in clinical practice. Although the exact molecular mechanisms …