Developmental Outcomes after Opioid Exposure in the Fetus and Neonate

J Fong, J Lewis, M Lam, K Kesavan - NeoReviews, 2024 - publications.aap.org
The overall prevalence of opiate use has been increasing, currently affecting approximately
0.6% of the global population and resulting in a significant proportion of infants being born …

Prenatal opioid exposure and neurodevelopmental outcomes

JJ Lee, N Saraiya, MW Kuzniewicz - Journal of Neurosurgical …, 2023 - journals.lww.com
The opioid epidemic in the United States has resulted in a significant increase in opioid use
disorder among pregnant women and a concomitant increase in the incidence of neonatal …

Prenatal exposure to opioids and neurodevelopment in infancy and childhood: a systematic review

AA Balalian, R Graeve, M Richter, A Fink… - Frontiers in …, 2023 - frontiersin.org
Aim This systematic review aims to estimate the relationship between prenatal exposure to
opioids and neurodevelopmental outcomes and examines potential sources of …

Neurodevelopmental Outcomes of Children Prenatally Exposed to Opioids and Other Substances

HE Jones, K Andringa, S Carroll, E Horton - Neonatal Opioid Withdrawal … - taylorfrancis.com
This chapter focuses on the myriad of factors that are known or suspected to cause
neurodevelopmental alterations in children to show the challenge with drawing a clear …

Prenatal opioid exposure: the next neonatal neuroinflammatory disease

LL Jantzie, JR Maxwell, JC Newville… - Brain, behavior, and …, 2020 - Elsevier
The rates of opioid use disorder during pregnancy have more than quadrupled in the last
decade, resulting in numerous infants suffering exposure to opioids during the perinatal …

Prenatal opioid exposure: neurodevelopmental consequences and future research priorities

E Conradt, T Flannery, JL Aschner, RD Annett… - …, 2019 - publications.aap.org
Neonatal opioid withdrawal syndrome (NOWS) has risen in prevalence from 1.2 per 1000
births in 2000 to 5.8 per 1000 births in 2012. Symptoms in neonates may include high …

Prenatal opioid exposure–increasing evidence of harm

H Mactier, R Hamilton - Early human development, 2020 - Elsevier
Prenatal opioid exposure adversely impacts upon fetal growth and places the newborn at
risk of neonatal opioid withdrawal. The severity and duration of opioid withdrawal cannot be …

The immediate and long-term effects of prenatal opioid exposure

E Yen, JM Davis - Frontiers in Pediatrics, 2022 - frontiersin.org
The opioid epidemic has adversely affected neonates and children, yet the mechanisms by
which it impacts this population are not well understood. Not only does prenatal opioid …

Infant neurodevelopmental outcomes of prenatal opioid exposure and polysubstance use

MH Labella, RD Eiden, AR Tabachnick… - Neurotoxicology and …, 2021 - Elsevier
Background Prenatal opioid exposure has been linked to adverse birth outcomes and
delays in infant development. Existing literature is limited by a simple group-differences …

[HTML][HTML] Early life stress and environmental influences on the neurodevelopment of children with prenatal opioid exposure

E Conradt, SE Crowell, BM Lester - Neurobiology of stress, 2018 - Elsevier
Prenatal opioid exposure has reached epidemic proportions. In the last 10 years, there has
been a 242% increase in the number of babies born with the drug withdrawal syndrome …