Rosuvastatin demonstrates greater reduction of low-density lipoprotein cholesterol compared with pravastatin and simvastatin in hypercholesterolaemic patients: a …

R Paoletti, M Fahmy, G Mahla… - Journal of …, 2001 - journals.sagepub.com
Background Rosuvastatin (Crestor), a new, highly efficacious statin, has demonstrated dose-
dependent low-density lipoprotein cholesterol (LDL-C) reductions of up to 65% in a dose …

Efficacy and safety of rosuvastatin 40 mg versus atorvastatin 80 mg in high-risk patients with hypercholesterolemia: results of the POLARIS study

LA Leiter, RS Rosenson, E Stein, JPD Reckless… - Atherosclerosis, 2007 - Elsevier
POLARIS investigated the efficacy and safety of rosuvastatin 40mg and atorvastatin 80mg in
high-risk patients with hypercholesterolemia. Patients (n= 871) were randomized to …

Efficacy and safety of rosuvastatin compared with pravastatin and simvastatin in patients with hypercholesterolemia: a randomized, double-blind, 52-week trial

WV Brown, HE Bays, DR Hassman, J McKenney… - American heart …, 2002 - Elsevier
Objective The primary objective of this trial was to compare the efficacy of rosuvastatin with
that of pravastatin and simvastatin for lowering low-density lipoprotein cholesterol (LDL-C) …

Efficacy and safety of rosuvastatin and atorvastatin in patients with hypercholesterolemia and a high risk of coronary heart disease: a randomized, controlled trial

GG Schwartz, MA Bolognese, BP Tremblay… - American Heart …, 2004 - Elsevier
BACKGROUND: This double-blind, multicenter, randomized trial compared rosuvastatin and
atorvastatin for reducing low-density lipoprotein cholesterol (LDL-C) in adults with …

Comparison of the efficacy and safety of rosuvastatin versus atorvastatin, simvastatin, and pravastatin across doses (STELLAR Trial)

PH Jones, MH Davidson, EA Stein, HE Bays… - The American journal of …, 2003 - Elsevier
The primary objective of this 6-week, parallel-group, open-label, randomized, multicenter
trial was to compare rosuvastatin with atorvastatin, pravastatin, and simvastatin across dose …

Effects of rosuvastatin and atorvastatin compared over 52 weeks of treatment in patients with hypercholesterolemia

AG Olsson, H Istad, O Luurila, L Ose, S Stender… - American Heart …, 2002 - Elsevier
Background Despite the demonstrated benefits of low-density lipoprotein cholesterol (LDL-
C) reduction in reducing the risk of coronary heart disease, many patients receiving lipid …

Efficacy of rosuvastatin compared with other statins at selected starting doses in hypercholesterolemic patients and in special population groups

JW Blasetto, EA Stein, WV Brown, R Chitra… - The American journal of …, 2003 - Elsevier
A total of 5 randomized, double-blind trials in patients with hypercholesterolemia were
prospectively designed to allow pooling of plasma lipid data after 12 weeks of treatment. The …

Comparison of the efficacy of rosuvastatin versus atorvastatin, simvastatin, and pravastatin in achieving lipid goals: results from the STELLAR trial

JM McKenney, PH Jones, MA Adamczyk… - … medical research and …, 2003 - Taylor & Francis
SUMMARY In the Statin Therapies for Elevated Lipid Levels compared Across doses to
Rosuvastatin (STELLAR) trial, the efficacy of rosuvastatin calcium (Crestor) was compared …

[HTML][HTML] Comparison of the efficacy and safety of rosuvastatin 10 mg and atorvastatin 20 mg in high-risk patients with hypercholesterolemia–Prospective study to …

MB Clearfield, J Amerena, JP Bassand, HRH García… - Trials, 2006 - Springer
Background Many patients at high risk of cardiovascular disease do not achieve
recommended low-density lipoprotein cholesterol (LDL-C) goals. This study compared the …

Rosuvastatin

CI Carswell, GL Plosker, B Jarvis - Drugs, 2002 - Springer
Abstract▴ Rosuvastatin is a hydroxymethylglutaryl coenzyme A (HMG-CoA) reductase
inhibitor used in the treatment of patients with dyslipidaemia. Rosuvastatin is not extensively …