Combined Tlr2 and Tlr4 deficiency increases radiation-induced pulmonary fibrosis in mice
A Paun, J Fox, V Balloy, M Chignard, ST Qureshi… - International Journal of …, 2010 - Elsevier
PURPOSE: To determine whether Toll-like receptor 2 or 4 genotype alters the lung response
to irradiation in C57BL/6 mice using a model developing a phenotype that resembles …
to irradiation in C57BL/6 mice using a model developing a phenotype that resembles …
Cytokines in human lung fibrosis
Y Martinet, O Menard, P Vaillant, JM Vignaud… - Toxicology-From Cells to …, 1996 - Springer
Cytokines in human lung fibrosis Page 1 Cytokines in human lung fibrosis Yves Martinet,
Olivier Menard, Pierre Vaillant, Jean-Michel Vignaud, and Nadine Martinet INSERM U 14 …
Olivier Menard, Pierre Vaillant, Jean-Michel Vignaud, and Nadine Martinet INSERM U 14 …
Cytokine expression by neutrophils and macrophages in vivo: Endotoxin induces tumor necrosis factor-alpha, macrophage inflammatory protein-2, interleukin-1beta …
Using a rat model of acute lung inflammation induced by intratracheal instillation of
lipopolysaccharide (LPS), we investigated the kinetics of mRNA expression and the …
lipopolysaccharide (LPS), we investigated the kinetics of mRNA expression and the …
Neutralization of the CXC chemokine, macrophage inflammatory protein-2, attenuates bleomycin-induced pulmonary fibrosis
MP Keane, JA Belperio, TA Moore… - The Journal of …, 1999 - journals.aai.org
Few studies have addressed the importance of vascular remodeling in the lung during the
development of bleomycin-induced pulmonary fibrosis. For fibroplasia and deposition of …
development of bleomycin-induced pulmonary fibrosis. For fibroplasia and deposition of …
Airway neutrophilia and chemokine mRNA expression in sulfur dioxide-induced bronchitis.
A Farone, S Huang, J Paulauskis… - American journal of …, 1995 - atsjournals.org
Airway inflammation in acute and chronic bronchitis includes a prominent neutrophil influx.
Using a rat model of sulfur dioxide (SO2)-induced bronchitis, we investigated the role of the …
Using a rat model of sulfur dioxide (SO2)-induced bronchitis, we investigated the role of the …
C‐C chemokine receptor 2 (CCR2) deficiency improves bleomycin‐induced pulmonary fibrosis by attenuation of both macrophage infiltration and production of …
T Okuma, Y Terasaki, K Kaikita… - The Journal of …, 2004 - Wiley Online Library
Macrophage infiltration is implicated in various types of pulmonary fibrosis. One important
pathogenetic process associated with pulmonary fibrosis is injury to basement membranes …
pathogenetic process associated with pulmonary fibrosis is injury to basement membranes …
Chemokine production during hypersensitivity pneumonitis
S Nance, R Cross, E Fitzpatrick - European journal of …, 2004 - Wiley Online Library
Hypersensitivity pneumonitis (HP) is an interstitial lung disease that develops following
repeated exposure to inhaled particulate antigens. Individuals with HP develop lymphocytic …
repeated exposure to inhaled particulate antigens. Individuals with HP develop lymphocytic …
The murine neutrophil‐chemoattractant chemokines LIX, KC, and MIP‐2 have distinct induction kinetics, tissue distributions, and tissue‐specific sensitivities to …
LE Rovai, HR Herschman… - Journal of leukocyte …, 1998 - Wiley Online Library
Lipopolysaccharide‐induced CXC chemokine (LIX) is a novel murine neutrophil‐
chemoattractant CXC chemokine cloned as a glucocorticoid‐attenuated response gene. We …
chemoattractant CXC chemokine cloned as a glucocorticoid‐attenuated response gene. We …
Macrophage inflammatory protein-1 alpha mediates lung leukocyte recruitment, lung capillary leak, and early mortality in murine endotoxemia.
TJ Standiford, SL Kunkel, NW Lukacs… - … (Baltimore, Md.: 1950 …, 1995 - journals.aai.org
Systemic exposure to LPS initiates a complex sequence of events resulting in organ-specific
leukocyte recruitment and end-organ injury. We hypothesized that macrophage …
leukocyte recruitment and end-organ injury. We hypothesized that macrophage …
Changes in histology and fibrogenic cytokines in irradiated colorectum of two murine strains
MW Skwarchuk, EL Travis - International Journal of Radiation Oncology …, 1998 - Elsevier
Purpose: A strain difference in the development of radiation-induced fibrosis of the
colorectum was recently observed. C57B1/6 mice developed colorectal obstruction with …
colorectum was recently observed. C57B1/6 mice developed colorectal obstruction with …