Bone homeostasis involves bone formation and bone resorption, which are processes that
maintain skeletal health. Oxidative stress is an independent risk factor, causing the …

Osteoporosis is a highly prevalent disorder characterized by the loss of bone mass and
microarchitecture deterioration of bone tissue, attributed to various factors, including …

Autophagy is an evolutionarily conserved intracellular process, in which domestic cellular
components are selectively digested for the recycling of nutrients and energy. This process …

Autophagy is an evolutionary conserved and highly regulated recycling process of cellular
wastes. Having a housekeeping role, autophagy through the digestion of domestic cytosolic …

Autophagy, a major catabolic pathway responsible of the elimination of damaged proteins
and organelles, is now recognized as an anti-aging process. In addition to its basal role in …

The skeletal system is the basis of the vertebral body composition, which affords stabilization
sites for muscle attachment, protects vital organs, stores mineral ions, supplies places to the …

Bone remodeling is a tightly controlled mechanism in which osteoblasts (OB), the cells
responsible for bone formation, osteoclasts (OC), the cells specialized for bone resorption …

Autophagy is an evolutionarily conserved intracellular process and is considered one of the
main catabolism pathways. In the process of autophagy, cells are digested nonselectively or …

Imbalances between bone resorption and formation lie at the root of disorders such as
osteoporosis, Paget's disease of bone (PDB), and osteopetrosis. Recently, genetic and …

It has been long realized that the immune and skeletal systems are closely linked. This
crosstalk, also known as osteoimmunology, is a primary process required for bone health …