Both subtypes of estrogen receptor (ER), ERα and ERβ, are normally present in the
mammary gland. The role of ERα as a prognostic marker in breast cancer is well established …

Purpose: Previous conflicting results about the prognostic significance of estrogen receptor
(ER)-β in breast cancer may be explained by contribution of isoforms, of which five exist. Our …

The role of estrogen (ER) and progesterone receptors (PR) in breast cancer is well
established. Identification of the second human estrogen receptor, the estrogen receptor β …

The assessment of the estrogen receptor (ER) α and the progesterone receptor (PgR) in
breast cancer tissues is important for discriminating between hormone-dependent and …

Clinical management of breast cancer is increasingly guided by assessment of tumor
phenotypic parameters. One of these is estrogen receptor (ER) status, currently defined by …

The estrogen receptor (ER)-β isoform has been recently identified to be distinct from ERα
isoform and regulates separate sets of genes, and can exert opposite signaling functions …

Background The prognostic role of estrogen receptor beta (ERβ) in early-stage breast
cancer is unclear. We performed a systematic review and meta-analysis to evaluate the …

The aim of the present study was to investigate the role of estrogen receptor (ER) β in the
prognosis of ERα‑positive breast cancer in postmenopausal women, and its effect on the …

Purpose: Endocrine therapies, such as tamoxifen, are commonly given to most patients with
estrogen receptor (ERα)–positive breast carcinoma but are not indicated for persons with …

BACKGROUND: In breast cancer, little is known about the consequences of co-expression
of ERα with the second estrogen receptor, ERβ, and its isoforms in light of their joint …