Novel enamine derivatives were synthesized from the reaction of lactone and chalcones and
their antiproliferative and cytotoxic activities against six cancer cell lines (eg, HeLa, HT29 …

The carboxylic acid functional group plays a fundamental role in the biochemistry of living
systems as well as in drug design by enhancing the hydrophilicity of drugs as well as their …

Derivatives of isatin have been reported to possess cytotoxic effects against different human
carcinoma cell lines. A series of new isatin-linked chalcones was synthesized starting from …

The β-diketone derivatives in plants exhibit biological activity due to tautomerism and
extended conjugation with the aromatic ring system. β-diketone derivatives;(Z)-3-(4-(4 …

The emodin anthraquinone derivatives are generally used in traditional Chinese medicine
due to their various pharmacological activities. In the present study, a series of emodin …

Herein we report design, synthesis, and anticancer activity of compounds 6a–h and 11a–j.
Compounds 6a–f were designed based on 3‐aminomethyl pyridine attached to different …

Background: Cancer is a group of diseases characterized by the uncontrolled growth and
spread of abnormal cells. If the spread is not controlled, it can result in death. Cancer is …

In this study, a series of novel β‑hydroxy ketone derivatives 3a-o were designed,
synthesized, and evaluated for their anticancer activity. The structure of these compounds …

Phenyl ethanol derivatives are well-known classes of drug molecules that play an important
role as effective substitute analogs to anticancer and antiviral agents. In this work …

Twenty derivatives of chalcones were synthesized and their anticancer activities were
estimated against both breast and liver cancer besides two human normal cell lines. Out of …