The understanding of the pathogenesis of pulmonary fibrosis continues to evolve. The initial
hypothetical model suggested chronic inflammation as the cause of pulmonary fibrosis …

Idiopathic pulmonary fibrosis (IPF) is a devastating condition that carries a prognosis worse
than that of many cancers. A recent classification of the idiopathic interstitial pneumonias …

Pulmonary fibrosis is the end stage of many diffuse parenchymal lung diseases. It is
characterised by excessive matrix formation leading to destruction of the normal lung …

There has been ongoing controversy related to what differentiates normal lung repair and
fibrosis. For example, the current prevailing concept has been that idiopathic forms of …

Idiopathic pulmonary fibrosis (IPF) is a devastating disease characterized by severe and
progressive scar formation in the gas-exchange regions of the lung. Despite years of …

Pulmonary fibrosis is a highly heterogeneous and lethal pathological process with limited
therapeutic options. Although research on the pathogenesis of pulmonary fibrosis has …

Idiopathic pulmonary fibrosis (IPF) is a unique type of chronic fibrosing lung disease of
unknown etiology. The sequence of the pathogenic mechanisms is unknown, but the …

Pulmonary fibrosis is characterized by lung inflammation and abnormal tissue repair,
resulting in the replacement of normal functional tissue with an abnormal accumulation of …

Fibrogenesis is an often-deadly process with increasing world-wide incidence and limited
therapeutic options. Pulmonary fibrogenesis involves remodeling of the distal airspace and …

Idiopathic pulmonary fibrosis is a progressive and usually fatal lung disease characterized
by fibroblast proliferation and extracellular matrix remodeling, which result in irreversible …