New mechanisms of pulmonary fibrosis
RM Strieter, B Mehrad - Chest, 2009 - Elsevier
The understanding of the pathogenesis of pulmonary fibrosis continues to evolve. The initial
hypothetical model suggested chronic inflammation as the cause of pulmonary fibrosis …
hypothetical model suggested chronic inflammation as the cause of pulmonary fibrosis …
Idiopathic pulmonary fibrosis: multiple causes and multiple mechanisms?
Idiopathic pulmonary fibrosis (IPF) is a devastating condition that carries a prognosis worse
than that of many cancers. A recent classification of the idiopathic interstitial pneumonias …
than that of many cancers. A recent classification of the idiopathic interstitial pneumonias …
The pathogenesis of pulmonary fibrosis: a moving target
WA Wuyts, C Agostini, KM Antoniou… - European …, 2013 - Eur Respiratory Soc
Pulmonary fibrosis is the end stage of many diffuse parenchymal lung diseases. It is
characterised by excessive matrix formation leading to destruction of the normal lung …
characterised by excessive matrix formation leading to destruction of the normal lung …
What differentiates normal lung repair and fibrosis? Inflammation, resolution of repair, and fibrosis
RM Strieter - Proceedings of the American Thoracic Society, 2008 - atsjournals.org
There has been ongoing controversy related to what differentiates normal lung repair and
fibrosis. For example, the current prevailing concept has been that idiopathic forms of …
fibrosis. For example, the current prevailing concept has been that idiopathic forms of …
Cellular mechanisms of tissue fibrosis. 7. New insights into the cellular mechanisms of pulmonary fibrosis
CE Barkauskas, PW Noble - American Journal of …, 2014 - journals.physiology.org
Idiopathic pulmonary fibrosis (IPF) is a devastating disease characterized by severe and
progressive scar formation in the gas-exchange regions of the lung. Despite years of …
progressive scar formation in the gas-exchange regions of the lung. Despite years of …
[HTML][HTML] Integrating mechanisms of pulmonary fibrosis
TA Wynn - The Journal of experimental medicine, 2011 - ncbi.nlm.nih.gov
Pulmonary fibrosis is a highly heterogeneous and lethal pathological process with limited
therapeutic options. Although research on the pathogenesis of pulmonary fibrosis has …
therapeutic options. Although research on the pathogenesis of pulmonary fibrosis has …
Idiopathic pulmonary fibrosis: new insights in its pathogenesis
Idiopathic pulmonary fibrosis (IPF) is a unique type of chronic fibrosing lung disease of
unknown etiology. The sequence of the pathogenic mechanisms is unknown, but the …
unknown etiology. The sequence of the pathogenic mechanisms is unknown, but the …
Molecular mechanisms of and possible treatment strategies for idiopathic pulmonary fibrosis
M Gharaee-Kermani, SH Phan - Current pharmaceutical design, 2005 - ingentaconnect.com
Pulmonary fibrosis is characterized by lung inflammation and abnormal tissue repair,
resulting in the replacement of normal functional tissue with an abnormal accumulation of …
resulting in the replacement of normal functional tissue with an abnormal accumulation of …
Emerging concepts in the pathogenesis of lung fibrosis
WD Hardie, SW Glasser, JS Hagood - The American journal of pathology, 2009 - Elsevier
Fibrogenesis is an often-deadly process with increasing world-wide incidence and limited
therapeutic options. Pulmonary fibrogenesis involves remodeling of the distal airspace and …
therapeutic options. Pulmonary fibrogenesis involves remodeling of the distal airspace and …
Idiopathic pulmonary fibrosis: prevailing and evolving hypotheses about its pathogenesis and implications for therapy
Idiopathic pulmonary fibrosis is a progressive and usually fatal lung disease characterized
by fibroblast proliferation and extracellular matrix remodeling, which result in irreversible …
by fibroblast proliferation and extracellular matrix remodeling, which result in irreversible …