Aortic event rate in the Marfan population: a cohort study

G Jondeau, D Detaint, F Tubach, F Arnoult, O Milleron… - Circulation, 2012 - Am Heart Assoc
Background—Optimal management, including timing of surgery, remains debated in Marfan
syndrome because of a lack of data on aortic risk associated with this disease. Methods and …

Survival and complication free survival in Marfan's syndrome: implications of current guidelines

M Groenink, TAJ Lohuis, JGP Tijssen, MSJ Naeff… - Heart, 1999 - heart.bmj.com
OBJECTIVE To evaluate survival and complication free survival in patients with Marfan's
syndrome and to assess the possible influence of recently revised guidelines for …

Aortic events in a nationwide Marfan syndrome cohort

KA Groth, K Stochholm, H Hove, K Kyhl… - Clinical Research in …, 2017 - Springer
Background Marfan syndrome is associated with morbidity and mortality due to aortic
dilatation and dissection. Preventive aortic root replacement has been the standard …

Causes of mortality in the Marfan syndrome (from a nationwide register study)

KA Groth, K Stochholm, H Hove, NH Andersen… - The American journal of …, 2018 - Elsevier
The Marfan syndrome (MFS) is strongly associated with aortic disease causing a high
prevalence of prophylactic aortic surgery, aortic dissection, and sudden death. The aim of …

Beyond the root: dilatation of the distal aorta in Marfan's syndrome

PM Engelfriet, E Boersma, JGP Tijssen, BJ Bouma… - Heart, 2006 - heart.bmj.com
Objective: To investigate dilatory changes of the aorta distal to the root in patients with
Marfan's syndrome. Methods and results: Data of 268 patients with Marfan's syndrome who …

Dissection in Marfan syndrome: the importance of the descending aorta

L Mimoun, D Detaint, D Hamroun, F Arnoult… - European heart …, 2011 - academic.oup.com
Aims To better characterize patients with Marfan syndrome who have survived an acute
aortic dissection and to estimate the risks of events in the descending aorta. Up until now …

The risk for type B aortic dissection in Marfan syndrome

AW den Hartog, R Franken, AH Zwinderman… - Journal of the American …, 2015 - jacc.org
Background: Aortic dissections involving the descending aorta are a major clinical problem
in patients with Marfan syndrome. Objectives: The purpose of this study was to identify …

Spectrum of aortic operations in 300 patients with confirmed or suspected Marfan syndrome

SA LeMaire, SA Carter, IV Volguina, AT Laux… - The Annals of thoracic …, 2006 - Elsevier
BACKGROUND: Cardiovascular disease is the main cause of morbidity and mortality in
patients with Marfan syndrome. Many patients with presumed Marfan syndrome do not meet …

Management of Marfan syndrome

JCS Dean - Heart, 2002 - heart.bmj.com
Marfan syndrome is a variable, autosomal dominant connective tissue disorder, affecting
mainly the cardiovascular system, eyes, and skeleton. The incidence is approximately 1 in …

Marfan syndrome: long-term survival and complications after aortic aneurysm repair

R Finkbohner, D Johnston, ES Crawford, J Coselli… - Circulation, 1995 - Am Heart Assoc
Background Development of surgical therapy for aortic aneurysms and dissections has led
to treatment of the life-threatening cardiovascular complications associated with Marfan …