Flexibility of gut microbiota in ageing individuals during dietary fiber long‐chain inulin intake

MBG Kiewiet, ME Elderman, S El Aidy… - Molecular nutrition & …, 2021 - Wiley Online Library
Scope During ageing, dysbiosis in the intestinal microbiota may occur and impact health.
There is a paucity of studies on the effect of fiber on the elderly microbiota and the flexibility …

Trehalose supplementation reduces hepatic endoplasmic reticulum stress and inflammatory signaling in old mice

MJ Pagliassotti, AL Estrada, WM Hudson, Y Wei… - The Journal of nutritional …, 2017 - Elsevier
The accumulation of damaged proteins can perturb cellular homeostasis and provoke aging
and cellular damage. Quality control systems, such as the unfolded protein response (UPR) …

[HTML][HTML] Impacts of gut microbiota alteration on age-related chronic liver diseases

S Adhikary, A Esmeeta, A Dey, A Banerjee… - Digestive and Liver …, 2023 - Elsevier
The gut microbiome and its metabolites are involved in developing and progressing liver
disease. Various liver illnesses, such as non-alcoholic fatty liver disease, alcoholic liver …

Healthspan and lifespan extension by fecal microbiota transplantation into progeroid mice

C Bárcena, R Valdés-Mas, P Mayoral, C Garabaya… - Nature medicine, 2019 - nature.com
The gut microbiome is emerging as a key regulator of several metabolic, immune and
neuroendocrine pathways,. Gut microbiome deregulation has been implicated in major …

Interactions between dietary polyphenols and aging gut microbiota: A review

S Davinelli, G Scapagnini - BioFactors, 2022 - Wiley Online Library
Aging induces significant shifts in the composition of gut microbiota associated with
decreased microbial diversity. Age‐related changes in gut microbiota include a loss of …

Gut microbiota and physical frailty through the mediation of sarcopenia

M Casati, E Ferri, D Azzolino, M Cesari… - Experimental …, 2019 - Elsevier
The changing physiology and lifestyle of older people affect the gut microbiota composition.
In particular, the age-related diet modifications can alter the gut microbiota biodiversity and …

Age-related changes in intestinal immunity and the microbiome

T Walrath, KU Dyamenahalli… - Journal of Leucocyte …, 2021 - academic.oup.com
The gastrointestinal (GI) tract is a vitally important site for the adsorption of nutrients as well
as the education of immune cells. Homeostasis of the gut is maintained by the interplay of …

Interplay of broccoli/broccoli sprout bioactives with gut microbiota in reducing inflammation in inflammatory bowel diseases

J Holman, M Hurd, PL Moses, GM Mawe… - The Journal of …, 2023 - Elsevier
Abstract Inflammatory Bowel Diseases (IBD) are chronic, reoccurring, and debilitating
conditions characterized by inflammation in the gastrointestinal tract, some of which can …

[HTML][HTML] The role of nutrition in enhancing immunity in aging

M Pae, SN Meydani, D Wu - Aging and disease, 2012 - ncbi.nlm.nih.gov
Aging is associated with declined immune function, particularly T cell-mediated activity,
which contributes to increased morbidity and mortality from infectious disease and cancer in …

The inflammatory status of the elderly: the intestinal contribution

EJ Schiffrin, JE Morley, A Donnet-Hughes… - … Molecular Mechanisms of …, 2010 - Elsevier
A common finding in the elderly population is a chronic subclinical inflammatory status that
coexists with immune dysfunction. These interconnected processes are of sufficient …