Biomaterial strategies for immunomodulation

NA Hotaling, L Tang, DJ Irvine… - Annual review of …, 2015 - annualreviews.org
Strategies to enhance, suppress, or qualitatively shape the immune response are of
importance for diverse biomedical applications, such as the development of new vaccines …

Targeted modulation of immune cells and tissues using engineered biomaterials

P Yousefpour, K Ni, DJ Irvine - Nature reviews bioengineering, 2023 - nature.com
Therapies modulating the immune system offer the prospect of treating a wide range of
conditions including infectious diseases, cancer and autoimmunity. Biomaterials can …

Biomaterials-mediated engineering of the immune system

C Backlund, S Jalili-Firoozinezhad… - Annual review of …, 2023 - annualreviews.org
Modulation of the immune system is an important therapeutic strategy in a wide range of
diseases, and is fundamental to the development of vaccines. However, optimally safe and …

Engineering vaccines and niches for immune modulation

A Purwada, K Roy, A Singh - Acta biomaterialia, 2014 - Elsevier
Controlled modulation of immune response, especially the balance between
immunostimulatory and immunosuppressive responses, is critical for a variety of clinical …

Immunologically effective biomaterials

Q Wei, Y Su, H Xin, L Zhang, J Ding… - ACS Applied Materials & …, 2021 - ACS Publications
Immunoregulation represents a booming field of biomaterial design. The unique physical
and chemical properties of biomaterials offer tremendous opportunities for development …

Biomaterials as local niches for immunomodulation

K Adu-Berchie, DJ Mooney - Accounts of chemical research, 2020 - ACS Publications
Conspectus A major function of the immune system is to detect threat from foreign invaders,
tissue damage, or cancer and to mount a counter response that resolves the threat, restores …

Biomaterials innovation for next generation ex vivo immune tissue engineering

A Singh - Biomaterials, 2017 - Elsevier
Primary and secondary lymphoid organs are tissues that facilitate differentiation of B and T
cells, leading to the induction of adaptive immune responses. These organs are present in …

Designing biomaterials with immunomodulatory properties for tissue engineering and regenerative medicine

JI Andorko, CM Jewell - Bioengineering & translational …, 2017 - Wiley Online Library
Recent research in the vaccine and immunotherapy fields has revealed that biomaterials
have the ability to activate immune pathways, even in the absence of other immune …

Tailoring materials for modulation of macrophage fate

J Li, X Jiang, H Li, M Gelinsky, Z Gu - Advanced Materials, 2021 - Wiley Online Library
Human immune system acts as a pivotal role in the tissue homeostasis and disease
progression. Immunomodulatory biomaterials that can manipulate innate immunity and …

Materials that harness and modulate the immune system

JS Lewis, K Roy, BG Keselowsky - MRS bulletin, 2014 - cambridge.org
Recently, biomaterial scientists have married materials engineering and immunobiology to
conceptualize new immunomodulatory materials. This special class of biomaterials can …