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The availability of drugs for use as antidepressants has expanded greatly in the past 2
decades. Not only has the number of drugs increased but so has the diversity in associated …

Knowledge of the pharmacologic actions of antidepressants enables the physician to
develop an appropriate rationale for the use of these medications in the medical setting. The …

Depressed patients and their physicians naturally expect that each new antidepressant that
reaches the market will represent a conceptual and therapeutic advance over previous …

An understanding of the clinical pharmacology of antidepressant agents is essential to
optimal prescribing. The following chapter outlines general principles that influence …

Historically, the clinician's choice of antidepressant agent has been determined largely by
consideration of tolerability, given the perception that the therapeutic efficacy of the various …

A wide variety of antidepressants are available today for treating major depressive disorder.
However, like all medical therapies, antidepressants have several limitations that clinicians …

Major depressive disorders affect an estimated 23 million US adults per year. While
antidepressants are effective in improving the symptoms of depression, side effects are an …

Depression is not only a common disorder, but also one that is readily treatable.
Antidepressant drugs play a major role in treatment, although concurrent use of …

Although options for pharmacologic treatment for depression have grown seemingly
exponentially over the past several decades, the current armamentarium of antidepressants …