Cost analysis of erlotinib versus chemotherapy for first-line treatment of non–small-cell lung cancer in frail elderly patients participating in a prospective phase 2 study …

C Chouaid, H Le Caer, R Corre, J Crequit, C Locher… - Clinical Lung Cancer, 2013 - Elsevier
Background A large proportion of elderly patients (> 70 years) with newly diagnosed NSCLC
are shown to be frail by a comprehensive geriatric assessment. This population is more …

Cost effectivenes of erlotinib versus chemotherapy for first-line treatment of non small cell lung cancer (NSCLC) in fit elderly patients participating in a prospective …

C Christos, LC Hervé, L Chrystelle, D Cecile, T Pascal… - BMC cancer, 2012 - Springer
Background The median age of newly diagnosed patients with non-small cell lung cancer
(NSCLC) is 67 years, and one-third of patients are older than 75 years. Elderly patients are …

Erlotinib for advanced non–small-cell lung cancer in the elderly: an analysis of the National Cancer Institute of Canada Clinical Trials Group Study BR. 21

P Wheatley-Price, K Ding, L Seymour… - Journal of Clinical …, 2008 - ascopubs.org
Purpose National Cancer Institute of Canada Clinical Trials Group Study BR. 21 established
erlotinib as a standard of care in patients with non–small-cell lung cancer (NSCLC) after …

Erlotinib treatment after platinum-based therapy in elderly patients with non-small-cell lung cancer in routine clinical practice–results from the ElderTac study

WM Brueckl, HJ Achenbach, JH Ficker, W Schuette - BMC cancer, 2018 - Springer
Background In this prospective non-interventional study, the effectiveness and tolerability of
erlotinib in elderly patients with non-small-cell lung cancer (NSCLC) after≥ 1 platinum …

Erlotinib for elderly patients with non‑small‑cell lung cancer: Subset analysis from a population‑based observational study by the Ibaraki Thoracic Integrative …

K Kurishima, H Satoh, T Kaburagi… - Molecular and …, 2013 - spandidos-publications.com
The incidence and mortality of lung cancer have increased worldwide over the last decades,
with an observed increased incidence particularly among elderly populations. It has not yet …

Erlotinib as 1st-line therapy for elderly patients (pts) with advanced non-small cell lung cancer (NSCLC)

O Merimsky, C Cheng, M Reck, S Au… - Journal of Clinical …, 2008 - ascopubs.org
19016 Background: The prognosis for elderly pts with advanced NSCLC is generally poor
due to significant co-morbidities that limit treatment options. Furthermore, aggressive …

Management of unfit older patients with advanced NSCLC

C Gridelli, P Maione, A Rossi, G Palazzolo… - Cancer Treatment …, 2009 - Elsevier
Lung cancer in the older individual is an increasingly common problem faced by the
oncologist. Elderly patients over 70years account about 40% of lung cancer patients …

Phase II trial of erlotinib in elderly patients (age> 70) with previously untreated advanced non-small cell lung cancer (NSCLC): An analysis of quality of life and …

DM Jackman, B Yeap, J Lucca, PA Ostler… - Journal of Clinical …, 2006 - ascopubs.org
7168 Background: Elderly patients derive survival benefit but significant toxicity from
chemotherapy for NSCLC. Erlotinib is associated with reasonable toxicity and has a survival …

Treating non-small-cell lung cancer first line with erlotinib monotherapy in elderly patients: discussion of a case series

M Reck - Oncology Research and Treatment, 2007 - karger.com
Non-small-cell lung cancer (NSCLC) predominantly occurs in the elderly, a group that has
been historically undertreated for various reasons such as perceived frailty and comorbidity …

Clinical retrospective analysis of erlotinib in the treatment of elderly patients with advanced non-small cell lung cancer

M Platania, F Agustoni, B Formisano, M Vitali… - Targeted …, 2011 - Springer
In order to evaluate the clinical efficacy and the safety profile of molecularly targeted
therapies as a palliative approach in elderly populations affected by advanced thoracic …