Introduction There are countless possibilities for drug combinations, which makes it
expensive and time-consuming to rely solely on clinical trials to determine the effects of each …

Combinatorial therapy may reduce drug side effects and improve drug efficacy, making
combination therapy a promising strategy to treat complex diseases. However, in the …

Synergistic drug combinations play an important role in the treatment of complex diseases.
The identification of effective drug combination is vital to further reduce the side effects and …

There is compelling evidence that synergistic drug combinations have become promising
strategies for combating complex diseases, and they have evident predominance comparing …

Abstract Background and Objective Due to the synergistic effects of drugs, drug combination
is one of the effective approaches for treating complex diseases. However, the identification …

Drug combination is now a hot research topic in the pharmaceutical industry, but experiment-
based methodologies are extremely costly in time and money. Many computational methods …

Background The discovery of anticancer drug combinations is a crucial work of anticancer
treatment. In recent years, pre-screening drug combinations with synergistic effects in a …

Combinatorial therapy is a promising strategy for combating complex diseases by improving
the efficacy and reducing the side effects. To facilitate the identification of drug combinations …

Combination therapy is a promising clinical treatment strategy for cancer and other complex
diseases. Multiple drugs can target multiple proteins and pathways, greatly improving the …

Motivation Drug combination therapies have shown promise in clinical cancer treatments.
However, it is hard to experimentally identify all drug combinations for synergistic interaction …