Functional differences between microglia and monocytes after ischemic stroke
Background The brain's initial innate response to stroke is primarily mediated by microglia,
the resident macrophage of the CNS. However, as early as 4 h after stroke, the blood–brain …
the resident macrophage of the CNS. However, as early as 4 h after stroke, the blood–brain …
[HTML][HTML] Neuroinflammatory responses in experimental and human stroke lesions
Neuroinflammation has been suggested as an attractive treatment target in stroke, since it
offers a broader therapeutic window in comparison to currently established thrombolytic …
offers a broader therapeutic window in comparison to currently established thrombolytic …
Inflammatory responses after ischemic stroke
JH DeLong, SN Ohashi, KC O'Connor… - Seminars in …, 2022 - Springer
Ischemic stroke generates an immune response that contributes to neuronal loss as well as
tissue repair. This is a complex process involving a range of cell types and effector …
tissue repair. This is a complex process involving a range of cell types and effector …
Dominant role of microglial and macrophage innate immune responses in human ischemic infarcts
T Zrzavy, J Machado‐Santos, S Christine… - Brain …, 2018 - Wiley Online Library
Inflammatory mechanisms, involving granulocytes, T‐cells, B‐cells, macrophages and
activated microglia, have been suggested to play a pathogenic role in experimental models …
activated microglia, have been suggested to play a pathogenic role in experimental models …
Immune pathways in etiology, acute phase, and chronic sequelae of ischemic stroke
Inflammation and immune mechanisms are crucially involved in the pathophysiology of the
development, acute damage cascades, and chronic course after ischemic stroke …
development, acute damage cascades, and chronic course after ischemic stroke …
Inflammatory mechanisms after ischemia and stroke
GH Danton, WD Dietrich - Journal of Neuropathology & …, 2003 - academic.oup.com
Inflammation has been implicated as a secondary injury mechanism following ischemia and
stroke. A variety of experimental models, including thromboembolic stroke, focal and global …
stroke. A variety of experimental models, including thromboembolic stroke, focal and global …
The inflammatory response in stroke
Q Wang, XN Tang, MA Yenari - Journal of neuroimmunology, 2007 - Elsevier
Recent works in the area of stroke and brain ischemia has demonstrated the significance of
the inflammatory response accompanying necrotic brain injury. Acutely, this response …
the inflammatory response accompanying necrotic brain injury. Acutely, this response …
Innate inflammatory responses in stroke: mechanisms and potential therapeutic targets
JY Kim, M Kawabori, MA Yenari - Current medicinal chemistry, 2014 - ingentaconnect.com
Stroke is a frequent cause of long-term disability and death worldwide. Ischemic stroke is
more commonly encountered compared to hemorrhagic stroke, and leads to tissue death by …
more commonly encountered compared to hemorrhagic stroke, and leads to tissue death by …
Immune cells after ischemic stroke onset: roles, migration, and target intervention
L Ao, YY Yan, L Zhou, C Li, WT Li, W Fang… - Journal of Molecular …, 2018 - Springer
Ischemic stroke is one of the leading health issues and the major cause of permanent
disability in adults worldwide. Energy depletion and hypoxia occurring after ischemic stroke …
disability in adults worldwide. Energy depletion and hypoxia occurring after ischemic stroke …
Inflammation and neural repair after ischemic brain injury
S Sakai, T Shichita - Neurochemistry International, 2019 - Elsevier
Stroke causes neuronal cell death and destruction of neuronal circuits in the brain and
spinal cord. Injury to the brain tissue induces sterile inflammation triggered by the …
spinal cord. Injury to the brain tissue induces sterile inflammation triggered by the …