Ischemic stroke is a leading cause of death and disability in developed countries. Yet, in
spite of substantial research and development efforts, no specific therapy for stroke is …

Stroke is the second leading cause of global death and is characterized by high rates of
mortality and disability. Oxidative stress is accompanied by other pathological processes …

Microglia, the major endogenous immune cells of the central nervous system, mediate
critical degenerative and regenerative responses in ischaemic stroke. Microglia become …

The innate immune system plays a dualistic role in the evolution of ischemic brain damage
and has also been implicated in ischemic tolerance produced by different conditioning …

Cerebral ischemia is caused by arterial occlusion due to a thrombus or an embolus. Such
occlusion induces multiple and concomitant pathophysiological processes that involve …

Ischemic stroke (IS) is one of the most fatal diseases. Neuroimmunity, inflammation, and
oxidative stress play important roles in various complex mechanisms of IS. In particular, the …

Ischemic stroke, caused by a sudden disruption of blood flow to the brain, is a leading cause
of death and exerts a heavy burden on both patients and public health systems. Currently …

Post-ischemic inflammation is an essential step in the progression of brain ischemia-
reperfusion injury. In this review, we focus on the post-ischemic inflammation triggered by …

This review covers the pathogenesis of ischemic stroke and future directions regarding
therapeutic options after injury. Ischemic stroke is a devastating disease process affecting …

Neuroinflammation underlies the etiology of multiple neurodegenerative diseases and
stroke. Our understanding of neuroinflammation has evolved in the last few years and major …