Clinical factors predicting treatment resistant depression: affirmative results from the European multicenter study
Objectives Clinical variables were investigated in the 'treatment resistant depression (TRD)‐
III'sample to replicate earlier findings by the European research consortium 'Group for the …
III'sample to replicate earlier findings by the European research consortium 'Group for the …
Genetic and clinical characteristics of treatment-resistant depression using primary care records in two UK cohorts
C Fabbri, SP Hagenaars, C John, AT Williams… - Molecular …, 2021 - nature.com
Abstract Treatment-resistant depression (TRD) is a major contributor to the disability caused
by major depressive disorder (MDD). Primary care electronic health records provide an …
by major depressive disorder (MDD). Primary care electronic health records provide an …
A clinical approach to treatment resistance in depressed patients: What to do when the usual treatments don't work well enough?
Background Major depressive disorder is a common, recurrent, disabling and costly disorder
that is often severe and/or chronic, and for which non-remission on guideline concordant first …
that is often severe and/or chronic, and for which non-remission on guideline concordant first …
Treatment-resistant depression
Treatment-resistant depression (TRD) is a common clinical occurrence among patients
treated for major depressive disorder. However, a clear consensus regarding the criteria …
treated for major depressive disorder. However, a clear consensus regarding the criteria …
Is treatment-resistant depression a unique subtype of depression?
A Fagiolini, DJ Kupfer - Biological Psychiatry, 2003 - Elsevier
Treatment-resistant depression (TRD) continues to represent a major challenge for treating
clinicians. This report reviews the relevant literature to evaluate whether TRD can be …
clinicians. This report reviews the relevant literature to evaluate whether TRD can be …
Treatment-resistant depression: critique of current approaches
C Wijeratne, P Sachdev - Australian & New Zealand Journal …, 2008 - journals.sagepub.com
The aim of the present study was to critically appraise current conceptual approaches;
demographic, neurobiological and clinical correlates; and management strategies of …
demographic, neurobiological and clinical correlates; and management strategies of …
The genetics of treatment-resistant depression: a critical review and future perspectives
Background One-third of depressed patients develop treatment-resistant depression with the
related sequelae in terms of poor functionality and worse prognosis. Solid evidence …
related sequelae in terms of poor functionality and worse prognosis. Solid evidence …
The impact of COMT gene polymorphisms on suicidality in treatment resistant major depressive disorder—a European multicenter study
Many association studies have reported associations between the catechol-O-
methyltransferase (COMT) gene and psychiatric disorders including major depression …
methyltransferase (COMT) gene and psychiatric disorders including major depression …
Risk factors for treatment resistance in unipolar depression: a systematic review
D Bennabi, B Aouizerate, W El-Hage, O Doumy… - Journal of affective …, 2015 - Elsevier
Background Treatment resistant depression is a complex disorder and an important source
of morbidity and mortality. Identification of risk factors of resistance may be useful to improve …
of morbidity and mortality. Identification of risk factors of resistance may be useful to improve …
Issues in treatment-resistant depression
MB Keller - Journal of Clinical Psychiatry, 2005 - psychiatrist.com
Major depressive disorder is a debilitating disease that imposes significant social and
economic burdens not only on patients but also on society. Although various treatment …
economic burdens not only on patients but also on society. Although various treatment …