P-selectin was shown to bind committed human hematopoietic progenitors (colony-forming
unit-granulocyte-macrophage [CFU-GM] and burst-forming unit-erythroid [BFU-E]) as …

The adhesive characteristics of hematopoietic stem and progenitor cells may partly regulate
their proliferation and differentiation and may be critical in the homing of transplanted stem …

Cellular interactions are critical for the regulation of hematopoiesis. The sialomucin PSGL-
1/CD162 mediates the attachment of mature leukocytes to P-selectin. We now show that …

Although both P-and E-selectin are constitutively expressed on bone marrow endothelial
cells, their role in the regulation of hematopoiesis has only recently been investigated. We …

OBJECTIVE: The two endothelial selectins, P-and E-selectin, are critically important for
adhesion and homing of hematopoietic progenitor cells (HPC) into the bone marrow. Little is …

P-selectin glycoprotein ligand-1 (PSGL-1) is a muclin-like glycoportein ligand for P-and E-
selectin on myeloid cells and a subset of lymphocytes. We used flow cytometry and …

The nature and exact function of selectin ligands involved in hematopoietic progenitor cell
(HPC) homing to the bone marrow (BM) are unclear. Using murine progenitor homing …

E-selectin plays a critical role in mediating tissue-specific homing of T cells into skin, and of
primitive hematopoietic progenitor cells (HPCs) into bone marrow (BM). Though it is known …

Human hematopoietic progenitor cells express L-selectin and also express PSGL-1, a
ligand for all selectins. Using a shear-based adhesion assay, a hematopoietic cell L-selectin …

Abstract P-selectin (CD62P) is a member of the selectin family of adhesion molecules
involved in the regulation of leukocyte traffic. P-selectin glycoprotein ligand-1 (PSGL-1) is a …