Candida albicans is a well-tolerated resident of human mucosal tissues. This implies that
host defense mechanisms cooperate to limit inflammation while controlling fungal burden …

The proinflammatory cytokine IL-1β plays an important role in antifungal immunity; however,
the mechanisms by which fungal pathogens trigger IL-1β secretion are unclear. In this study …

Candida sp. are opportunistic fungal pathogens that colonize the skin and oral cavity and,
when overgrown under permissive conditions, cause inflammation and disease. Previously …

Candida albicans is an opportunistic fungal pathogen causing life-threatening mucosal and
systemic infections in immunocompromised humans. Using a murine model of mucosal …

Candida albicans and C. parapsilosis are human pathogens causing severe infections. The
NLRP3 inflammasome plays a crucial role in host defence against C. albicans, but it has …

The Nlrp3 inflammasome has been proposed to play an important role in antifungal host
defense. However, studies exploring the role of the inflammasome in antifungal host …

Candida albicans is an opportunistic fungal pathogen that can cause life-threatening
infections, particularly in immunocompromised patients. C. albicans induced activation of the …

Candida albicans is an opportunistic fungal pathogen that colonizes human gastro-intestinal
mucosal tissues. Its effect on the immune response in intestinal epithelial cells and on the …

The relationship between host and opportunistic pathogen is a tenuous one and an
injudicious response to pathogen-associated molecular patterns may result in a hostile …

Candida albicans is part of the normal microbiota in most healthy individuals. However, it
can cause opportunistic infections if host defenses are breached, with symptoms ranging …