Rhus coriaria induces autophagic and apoptotic cell death in pancreatic cancer cells

Y El Mahi, ZN Nizami, AF Wali, A Al Neyadi… - Frontiers in …, 2024 - frontiersin.org
Background: Pancreatic cancer is a leading cause of cancer-related mortality worldwide with
increasing global incidence. We previously reported the anticancer effect of Rhus coriaria …

Epieriocalyxin A induces cell apoptosis through JNK and ERK1/2 signaling pathways in colon cancer cells

Z Wang, Z Xu, Z Niu, B Liang, J Niu - Cell biochemistry and biophysics, 2015 - Springer
Colorectal cancer is one of the most commonly diagnosed cancers in the world. Currently,
drug resistance of cancer cell to chemotherapy is a major cause for cancer recurrence and …

Brusatol inhibits the growth of prostate cancer cells and reduces HIF-1α/VEGF expression and glycolysis under hypoxia

M Wang, L Dai, W Yan, Y Chen, Y Wang - … and Safety of Crops & Foods, 2022 - qascf.com
Prostate cancer (PCa) has a high rate of morbidity and mortality, which urges us to find a
unique and effective drug for treatment. Brusatol, a triterpenoid-degraded derivative …

Oleanolic acid inhibits cell survival and proliferation of prostate cancer cells in vitro and in vivo through the PI3K/Akt pathway

X Li, Y Song, P Zhang, H Zhu, L Chen, Y Xiao, Y Xing - Tumor Biology, 2016 - Springer
Oleanolic acid (OA) is a naturally occurring pentacyclic triterpenoid and possesses diverse
pharmacological activities, including anti-cancer effects that have been confirmed in multiple …

Aloysia citrodora essential oil inhibits melanoma cell growth and migration by targeting HB-EGF-EGFR signaling

Y Salama, N Jaradat, K Hattori, B Heissig - International journal of …, 2021 - mdpi.com
Patients diagnosed with melanoma have a poor prognosis due to regional invasion and
metastases. The receptor tyrosine kinase epidermal growth factor receptor (EGFR) is found …

Natural product Eriocalyxin B suppressed triple negative breast cancer metastasis both in vitro and in vivo

L Gou, GGL Yue, JKM Lee, PT Puno… - Biochemical …, 2023 - Elsevier
Breast cancer is the most commonly diagnosed cancer among women, and its metastasis to
distant organs accounts for the majority of death. Eriocalyxin B (Eri B), an ent-kaurane …

Huaier suppresses proliferative and metastatic potential of prostate cancer PC3 cells via downregulation of Lamin B1 and induction of autophagy

A Yang, Y Zhao, Y Wang, X Zha… - Oncology …, 2018 - spandidos-publications.com
Prostate cancer is one of the most common malignancies occurring in males. Although large
advances have been made in the pathogenesis of prostate cancer, the development of …

Inhibition of lipogenesis and induction of apoptosis by valproic acid in prostate cancer cells via the C/EBPα/SREBP-1 pathway

B Pang, J Zhang, X Zhang, J Yuan… - Acta Biochimica et …, 2021 - academic.oup.com
Lipid metabolism reprogramming is now accepted as a new hallmark of cancer. Hence,
targeting the lipogenesis pathway may be a potential avenue for cancer treatment. Valproic …

Litchi seed extracts diminish prostate cancer progression via induction of apoptosis and attenuation of EMT through Akt/GSK-3β signaling

H Guo, H Luo, H Yuan, Y Xia, P Shu, X Huang, Y Lu… - Scientific reports, 2017 - nature.com
Abstract Litchi (Litchi chinensisSonnnerat, Sapindaceae), known as Chinese Cherry, is a
subtropical fruit tree originating from southern China. Litchi seed extracts have diverse …

Erianin induces G2/M-phase arrest, apoptosis, and autophagy via the ROS/JNK signaling pathway in human osteosarcoma cells in vitro and in vivo

H Wang, T Zhang, W Sun, Z Wang, D Zuo, Z Zhou… - Cell death & …, 2016 - nature.com
Erianin, a natural product derived from Dendrobium chrysotoxum, has exhibited potential
antitumor activity in various malignancies, including hepatocarcinoma, melanoma, and …