[HTML][HTML] Angiotensin II type 1 receptor expression in ovarian cancer and its correlation with tumour angiogenesis and patient survival

K Ino, K Shibata, H Kajiyama, E Yamamoto… - British Journal of …, 2006 - nature.com
Angiotensin II, a main effector peptide in the renin–angiotensin system, acts as a growth-
promoting and angiogenic factor via type 1 angiotensin II receptors (AT 1 R). We have …

Functional expression of the angiotensin II type1 receptor in human ovarian carcinoma cells and its blockade therapy resulting in suppression of tumor invasion …

T Suganuma, K Ino, K Shibata, H Kajiyama… - Clinical Cancer …, 2005 - AACR
Purpose: Angiotensin II is a bioactive peptide of the renin-angiotensin system, acting not
only as a vasoconstrictor but also as a growth promoter via angiotensin II type 1 receptors …

Association between AT1 and AT2 angiotensin II receptor expression with cell proliferation and angiogenesis in operable breast cancer

O Arrieta, C Villarreal-Garza, G Vizcaíno, B Pineda… - Tumor Biology, 2015 - Springer
Angiotensin II (ANGII) has been associated with vascular proliferation in tumor and non-
tumor models through its receptors AT1 and AT2. Our objective was to determine AT1 and …

Potential role of renin–angiotensin-system for tumor angiogenesis in receptor negative breast cancer

D Herr, M Rodewald, HM Fraser, G Hack, R Konrad… - Gynecologic …, 2008 - Elsevier
OBJECTIVE: This study examined the potential role of Angiotensin II for the regulation of
angiogenesis associated genes in receptor positive and negative human breast cancer …

Deficiency or blockade of angiotensin II type 2 receptor delays tumorigenesis by inhibiting malignant cell proliferation and angiogenesis

N Clere, I Corre, S Faure, AL Guihot… - … journal of cancer, 2010 - Wiley Online Library
Despite significant expression level in cancer cells, the role of the angiotensin II Type 2
receptor (AT2R) in cancer progression remains poorly understood. We aimed to investigate …

Angiotensin II type 1 receptor antagonists inhibit cell proliferation and angiogenesis in breast cancer

X Chen, Q Meng, Y Zhao, M Liu, D Li, Y Yang, L Sun… - Cancer letters, 2013 - Elsevier
Angiotensin II type 1 receptor (AT1R) promotes tumor invasion, migration, metastasis and
angiogenesis. We explored the potential antitumor effects of AT1R antagonists in breast …

[HTML][HTML] Roles for host and tumor angiotensin II type 1 receptor in tumor growth and tumor-associated angiogenesis

N Imai, T Hashimoto, M Kihara, S Yoshida… - Laboratory …, 2007 - Elsevier
Angiotensin II (AII) is a multifunctional bioactive peptide, and host renin-angiotensin system
(RAS) is closely associated with tumor growth. Recent reports have described that AII is a …

Role of two types of angiotensin II receptors in colorectal carcinoma progression

L Zhou, Y Luo, S Sato, E Tanabe, M Kitayoshi… - Pathobiology, 2014 - karger.com
Abstract Angiotensin II (Ang-II) is a bioactive peptide associated closely with the progression
and metastasis of colorectal cancer (CRC). We examined the expression and role of 2 Ang-II …

Local angiotensin II-generation in human gastric cancer: Correlation with tumor progression through the activation of ERK1/2, NF-κB and survivin

J Kinoshita, S Fushida, S Harada… - International …, 2009 - spandidos-publications.com
Angiotensin II is a main effector peptide in renin-angiotensin system, acting as a growth
promoter via angiotensin II type 1 (AT1) receptor. The present study examined intrinsic …

Angiotensin type 1a receptor signaling-dependent induction of vascular endothelial growth factor in stroma is relevant to tumor-associated angiogenesis and tumor …

M Fujita, I Hayashi, S Yamashina, A Fukamizu… - …, 2005 - academic.oup.com
Angiotensin II is a multi-functional bioactive peptide and recent reports have suggested that
angiotensin II is a proangiogenic growth factor. A retrospective cohort study revealed that …