Abstract Background The neurobiology of Autism Spectrum Disorder (ASD) is still unknown.
Alteration in glutamate metabolism might translate into an imbalance of the …

Over the last few years, awareness of autism spectrum disorder (ASD) in adults has
increased. The precise etiology of ASD is still unresolved. Animal research, genetic and …

Dysfunctional glutamatergic neurotransmission has been implicated in autism spectrum
disorder (ASD). However, relatively few studies have directly measured brain glutamate in …

The excitatory‐inhibitory imbalance hypothesis postulates dysregulation of the gamma‐
aminobutyric acid (GABA) and glutamate (Glu) neurotransmitter systems as a common …

The pilot study aimed at examining the neural glutamatergic activity in autism. Seven
adolescent males (mean age: 14±1.8; age range: 12–17 years) with intact intellectual …

Neuroimaging studies have uncovered structural and functional alterations in the cingulate
cortex in individuals with autism spectrum disorders (ASD). Such abnormalities may underlie …

Recent research in autism spectrum disorder (ASD) has aroused interest in anterior
cingulate cortex and in the neurometabolite glutamate. We report two studies of pregenual …

Increased excitatory neuronal tones have been implicated in autism, but its mechanism
remains elusive. The amplified glutamate signals may arise from enhanced glutamatergic …

Objective: An imbalance of excitatory and inhibitory neurotransmission in autism spectrum
disorder (ASD) has been proposed. We compared glutamate (Glu), glutamine (Gln), and γ …

The nature of neurochemical changes in autism spectrum disorder (ASD) remains
controversial. We compared medial prefrontal cortex (mPFC) neurochemistry of twenty high …