Decreased GABAB receptors in the cingulate cortex and fusiform gyrus in Autism

AL Oblak, TT Gibbs, GJ Blatt - Journal of neurochemistry, 2010 - Wiley Online Library
J. Neurochem.(2010) 114, 1414–1423. Abstract Autism is a behaviorally defined
neurodevelopmental disorder and among its symptoms are disturbances in face and …

Volumetric analysis and three-dimensional glucose metabolic mapping of the striatum and thalamus in patients with autism spectrum disorders

MM Haznedar, MS Buchsbaum… - American Journal of …, 2006 - Am Psychiatric Assoc
Objective: In patients with autism, behavioral deficits as well as neuroimaging studies of the
anterior cingulate cortex suggest ventral rather than dorsal striatal and thalamic …

GABAARα2 is decreased in the axon initial segment of pyramidal cells in specific areas of the prefrontal cortex in autism

T Hong, C Falcone, B Dufour, S Amina, RP Castro… - Neuroscience, 2020 - Elsevier
Abstract Some forms of Autism Spectrum Disorder, a neurodevelopmental syndrome
characterized by impaired communication and social skills as well as repetitive behaviors …

Another step toward understanding brain functional connectivity alterations in autism: An Editorial Highlight for “Neurobiological substrates underlying corpus …

F Giona, J Pagano, C Verpelli… - Journal of …, 2021 - Wiley Online Library
Various neuroimaging approaches have reported alterations in brain connectivity in patients
with autism spectrum disorder (ASD). Nevertheless, specific cellular and molecular …

Functional deficits of the attentional networks in autism

J Fan, S Bernardi, NT Van Dam… - Brain and …, 2012 - Wiley Online Library
Attentional dysfunction is among the most consistent observations of autism spectrum
disorders (ASD). However, the neural nature of this deficit in ASD is still unclear. In this …

Proton magnetic resonance spectroscopic imaging of the brain in childhood autism

JG Levitt, J O'Neill, RE Blanton, S Smalley, D Fadale… - Biological …, 2003 - Elsevier
BACKGROUND: Autism is a developmental disorder of unknown neurologic basis. Based
on prior work, we used proton magnetic resonance spectroscopic imaging (1H-MRSI) to …

Decreased number and increased activation state of astrocytes in gray and white matter of the prefrontal cortex in autism

G Vakilzadeh, C Falcone, B Dufour, T Hong… - Cerebral …, 2022 - academic.oup.com
The cerebral cortex presents with alterations in the number of specific cell types in autism
spectrum disorder (ASD). Astrocytes have many functions in the brain including a role in …

GABAergic activity in autism spectrum disorders: an investigation of cortical inhibition via transcranial magnetic stimulation

PG Enticott, HA Kennedy, NJ Rinehart, BJ Tonge… - …, 2013 - Elsevier
Mounting evidence suggests a possible role for γ-aminobutyric acid (GABA) in the
neuropathophysiology of autism spectrum disorders (ASD), but the extent of this impairment …

Brain anatomy of autism spectrum disorders II. Focus on amygdala

M Bellani, S Calderoni, F Muratori… - … and psychiatric sciences, 2013 - cambridge.org
This brief review encompasses the key findings of structural Magnetic Resonance Imaging
(sMRI) research on amygdala volume in autism spectrum disorders (ASD). We also highlight …

[HTML][HTML] Thalamic and prefrontal GABA concentrations but not GABAA receptor densities are altered in high-functioning adults with autism spectrum disorder

LK Fung, RE Flores, M Gu, KL Sun, D James… - Molecular …, 2021 - nature.com
The gamma aminobutyric acid (GABA) neurotransmission system has been implicated in
autism spectrum disorder (ASD). Molecular neuroimaging studies incorporating …