Objective.—To determine whether a nutritional supplement of selenium will decrease the
incidence of cancer. Design.—A multicenter, double-blind, randomized, placebo-controlled …

Abstract The Nutritional Prevention of Cancer Trial was a double-blind, randomized, placebo-
controlled clinical trial designed to test whether selenium as selenized yeast (200 μg daily) …

The hypothesis that a dietary supplement of selenium (Se) may reduce cancer risk was
tested experimentally in humans. Patients with histories of basal/squamous cell carcinomas …

Nonexperimental studies suggest that individuals with higher selenium (Se) status are at
decreased risk of cancer. The Nutritional Prevention of Cancer (NPC) study randomized …

Abstract The Nutritional Prevention of Cancer Trial was a randomized, clinical trial designed
to evaluate the efficacy of selenium asselenized yeast (200 μg daily) in preventing …

Although experimental studies in animals show that selenium may prevent cancer, case‐
control studies of internal human cancers have been difficult to interpret because neoplastic …

Studies examining the relationship between dietary selenium intake and risk of various
cancers have shown that low selenium intake is associated with higher cancer rates. A …

Selenium supplementation has been shown for many years to work as an anticarcinogenic
agent both in epidemiology and in in vitro studies. Selenium supplementation has recently …

Evidence from epidemiological studies and a human intervention trial indicates that
selenium (Se) may have chemopreventive activity in humans. This report summarizes a …

The relation between selenium and cancer has been one of the most hotly debated topics in
human health over the last decades. Early observational studies reported an inverse relation …