Improvement, scaling-up, and downstream analysis of exosome production

D Jafari, S Malih, M Eini, R Jafari… - Critical reviews in …, 2020 - Taylor & Francis
Exosomes are the most researched extracellular vesicles. In many biological, physiological,
and pathological studies, they have been identified as suitable candidates for treatment and …

Exosomes as reconfigurable therapeutic systems

RS Conlan, S Pisano, MI Oliveira, M Ferrari… - Trends in molecular …, 2017 - cell.com
Historically, small molecules, including steroid hormones and cytokines, have been
attributed a role in paracrine and endocrine signaling, and now include a new player …

Trends in research on exosomes in cancer progression and anticancer therapy

D Sinha, S Roy, P Saha, N Chatterjee, A Bishayee - Cancers, 2021 - mdpi.com
Simple Summary Intensive research in the field of cancer biology has discovered a unique
mode of interplay between cells via extracellular bioactive vesicles called exosomes …

Challenges in the development and establishment of exosome-based drug delivery systems

J Wang, D Chen, EA Ho - Journal of Controlled Release, 2021 - Elsevier
Exosomes are extracellular vesicles released from cells and are characterized by a lipid
bilayer membrane encapsulating a variety of biological molecules such as nucleic acids or …

Biological functions and current advances in isolation and detection strategies for exosome nanovesicles

K Boriachek, MN Islam, A Möller, C Salomon… - Small, 2018 - Wiley Online Library
Abstract Exosomes are nanoscale (≈ 30–150 nm) extracellular vesicles of endocytic origin
that are shed by most types of cells and circulate in bodily fluids. Exosomes carry a specific …

Exosomes: from garbage bins to promising therapeutic targets

M H. Rashed, E Bayraktar, G K. Helal… - International journal of …, 2017 - mdpi.com
Intercellular communication via cell-released vesicles is a very important process for both
normal and tumor cells. Cell communication may involve exosomes, small vesicles of …

Exosome engineering for efficient and targeted drug delivery: Current status and future perspective

F Malekian, A Shamsian, SP Kodam… - The Journal of …, 2023 - Wiley Online Library
Exosomes are membrane‐bound vesicles that are released by most cells. They carry
nucleic acids, cytokines, growth factors, proteins, lipids, and metabolites. They are …

Exosomes: the future of biomarkers in medicine

F Properzi, M Logozzi, S Fais - Biomarkers in medicine, 2013 - Taylor & Francis
Exosomes are nanovesicles secreted into the extracellular environment upon internal
vesicle fusion with the plasma membrane. The molecular content of exosomes is a …

Exosomes, a new star for targeted delivery

H Chen, L Wang, X Zeng, H Schwarz… - Frontiers in cell and …, 2021 - frontiersin.org
Exosomes are cell-secreted nanoparticles (generally with a size of 30–150 nm) bearing
numerous biological molecules including nucleic acids, proteins and lipids, which are …

Exosomes and cancer: from molecular mechanisms to clinical applications

A Jafari, A Babajani, M Abdollahpour-Alitappeh… - Medical Oncology, 2021 - Springer
Exosomes are extracellular nanovesicles secreted from almost all types of normal and
cancer cells. Collective evidence suggests that exosomes participate in cell–cell …