Oxytocin and stress-related disorders: neurobiological mechanisms and treatment opportunities

LM Sippel, CE Allington, RH Pietrzak… - Chronic …, 2017 - journals.sagepub.com
Novel pharmacotherapies that improve outcomes for individuals with stress-related
psychiatric disorders are needed. The neurohormone oxytocin (OT) is a promising candidate …

[HTML][HTML] Intranasal oxytocin: miracle cure after trauma?

M Olff, M Van Zuiden, SBJ Koch, L Nawijn… - European Journal of …, 2015 - Taylor & Francis
Background: In popular media and on Internet, the neuropeptide oxytocin is often advertised
as a miracle drug that cures all types of disorders, reduces stress, saves marriages, all …

Oxytocin and anxiety disorders: translational and therapeutic aspects

WJ Naja, MP Aoun - Current psychiatry reports, 2017 - Springer
Abstract Purpose of Review This review aims to evaluate the most recent literature
examining the oxytocin (OXT) system's role in human anxiety by surveying various fields of …

Oxytocin effects on the human brain: findings, questions, and future directions

O Weisman, R Feldman - Biological Psychiatry, 2013 - biologicalpsychiatryjournal.com
Since the discovery that intranasal administration of neuro-peptides can have a direct impact
on the human brain, extant research has been devoted to understanding the effects of …

Oxytocin and psychotherapy: a pilot study of its physiological, behavioral and subjective effects in males with depression

K MacDonald, TM MacDonald, M Brüne, K Lamb… - …, 2013 - Elsevier
Individual psychotherapy is an important treatment for a number of psychiatric conditions
and involves a unique form of human attachment. This raises the question of whether …

[HTML][HTML] Oxytocin and major depressive disorder: experimental and clinical evidence for links to aetiology and possible treatment

DA Slattery, ID Neumann - Pharmaceuticals, 2010 - mdpi.com
Affective disorders represent the most common psychiatric diseases, with substantial co-
morbidity existing between major depressive disorders (MDD) and anxiety disorders. The …

[HTML][HTML] Oxytocin in general anxiety and social fear: a translational approach

ID Neumann, DA Slattery - Biological psychiatry, 2016 - Elsevier
The neuropeptide oxytocin (OXT) has been revealed as a profound anxiolytic and antistress
factor of the brain, besides its many prosocial and reproductive effects. Therefore, there is …

The role of the oxytocin system in anxiety disorders

S Yoon, YK Kim - Anxiety Disorders: Rethinking and Understanding …, 2020 - Springer
Oxytocin, a neuropeptide synthesized by the hypothalamus, plays a central role in human
social behavior, social cognition, anxiety, mood, stress modulation, and fear learning and …

Intranasal oxytocin as a potential therapeutic strategy in post-traumatic stress disorder: A systematic review

G Giovanna, S Damiani, L Fusar-Poli… - …, 2020 - Elsevier
Abstract Treatment options for Posttraumatic Stress Disorder (PTSD) are limited in terms of
available drugs and the success of psychotherapeutic interventions. Oxytocin is a peptide …

Oxytocin facilitates the sensation of social stress

M Eckstein, D Scheele, K Weber… - Human brain …, 2014 - Wiley Online Library
Essentially all social species experience social stress which can be a catalyst for detriments
in mental and physical health. The neuropeptide oxytocin (OXT) has been shown to produce …