Abstract Sinomenine (7, 8‐didehydro‐4‐hydroxy‐3, 7‐dimethoxy‐17‐methylmorphinan‐6‐
one) is a pure alkaloid extracted from the Chinese medical plant. In this report a liquid …

Background/purpose: For microdialysis studies in the skin, laboratory‐made linear probes
are often used. The application of the microdialysis technique to the investigation of …

Aim: To improve and validate analytical methods based on HPLC and liquid
chromatography coupled to electrospray ionization tandem mass spectrometry (LC-ESI …

A simple HPLC method has been developed for determination of sinomenine in dog plasma
and has been used to evaluate the pharmacokinetics of sinomenine tablets in dogs …

A RP-HPLC method was developed to determine the concentrations of sinomenine HCl in
serum and urine and its pharmacokinetics was studied in healthy volunteers. C18H37 …

[Pharmacokinetics of sinomenine by HPLC]. - Abstract - Europe PMC Sign in | Create an
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Sinomenine is an active ingredient extracted from herb medicine, which has been
prescribed to treat rheumatoid arthritis in clinics. The present work was to develop a simple …

A sensitive, precise and selective ultra-high performance liquid chromatography method
coupled with triple-quadrupole mass spectrometry was developed and validated for the …

Sinomenine, an alkaloid derived from the Chinese medical plant Sinomenium acutum, was
studied with regard to its pharmacokinetics and tissue distribution in rats, and to its protein …

BACKGROUND: Sinomenine is a pure alkaloid with a variety of pharmacological actions
including anti-inflammation, immuno-suppression, analgesia, antihypertension, and …