Despite major advances in medical, catheter-based or surgical treatment, cardiovascular
diseases such as peripheral artery disease and coronary artery disease still cause …

Therapeutic angiogenesis, that is, the generation of new vessels by delivery of specific
factors, is required both for rapid vascularization of tissue-engineered constructs and to treat …

VEGF (vascular endothelial growth factor) is the master regulator of blood vessel growth.
However, it displayed substantial limitations when delivered as a single gene to restore …

Despite the enormous progress made in terms of prevention and early intervention, a
pressing need remains to develop innovative therapeutic strategies for ischemic …

Therapeutic angiogenesis constitutes an alternative treatment for patients with extensive
tissue ischaemia in whom primary vascular reconstruction procedures are not feasible or …

Therapeutic angiogenesis is a novel approach to the treatment of coronary and peripheral
vascular disease not amenable to standard revascularization techniques. Vascular …

Abstract Vascular Endothelial Growth Factor (VEGF) is the most potent and ubiquitous
vascular growth factor known to date. Yet, prior to its description as a secreted mitogen for …

Therapeutic angiogenesis improves tissue ischemia by supplementing and supporting the
intrinsic process of angiogenesis. Besides direct administration of angiogenic growth factor …

Since the discovery of vascular endothelial growth factor (VEGF), therapeutic angiogenesis
has attracted interest as an alternative treatment for ischaemic heart and peripheral disease …

The formation of new blood vessels, called angiogenesis, is an essential pathophysiological
process in which several families of regulators have been implicated. Among these, vascular …