Effective therapies for obesity require invasive surgical and endoscopic interventions or high
patient adherence, making it challenging for patients with obesity to effectively manage their …

Improvements in ingestible electronics with the capacity to sense physiological and
pathophysiological states have transformed the standard of care for patients. Yet, despite …

The strong peristaltic contraction of the stomach facilitates mixing and emptying of ingested
food, which occurs rhythmically at approximately 3 cycles/min (cpm) in humans. Generally …

The gut-brain axis, which is mediated via enteric and central neurohormonal signaling, is
known to regulate a broad set of physiological functions from feeding to emotional behavior …

Devices interfacing with biological tissues can provide valuable insights into function,
disease, and metabolism through electrical and mechanical signals. However, certain …

Obesity is a significant health concern that often leads to metabolic dysfunction and chronic
diseases. This study introduces a novel approach to combat obesity using orally ingested …

Eating and drinking generate sequential mechanosensory signals along the digestive tract.
These signals are communicated to the brain for the timely initiation and regulation of …

Ingestible electronics have the capacity to transform our ability to effectively diagnose and
potentially treat a broad set of conditions. Current applications could be significantly …

Ingestible electronic devices enable noninvasive evaluation and diagnosis of pathologies in
the gastrointestinal (GI) tract but generally cannot therapeutically interact with the tissue wall …

Obesity remains prevalent in the US. One potential treatment is vagus nerve stimulation
(VNS), which activates the sensory afferents innervating the stomach that convey stomach …