A vibrating ingestible bioelectronic stimulator modulates gastric stretch receptors for illusory satiety
Effective therapies for obesity require invasive surgical and endoscopic interventions or high
patient adherence, making it challenging for patients with obesity to effectively manage their …
patient adherence, making it challenging for patients with obesity to effectively manage their …
Flexible piezoelectric devices for gastrointestinal motility sensing
Improvements in ingestible electronics with the capacity to sense physiological and
pathophysiological states have transformed the standard of care for patients. Yet, despite …
pathophysiological states have transformed the standard of care for patients. Yet, despite …
Self-powered coiled carbon-nanotube yarn sensor for gastric electronics
The strong peristaltic contraction of the stomach facilitates mixing and emptying of ingested
food, which occurs rhythmically at approximately 3 cycles/min (cpm) in humans. Generally …
food, which occurs rhythmically at approximately 3 cycles/min (cpm) in humans. Generally …
Bioinspired, ingestible electroceutical capsules for hunger-regulating hormone modulation
The gut-brain axis, which is mediated via enteric and central neurohormonal signaling, is
known to regulate a broad set of physiological functions from feeding to emotional behavior …
known to regulate a broad set of physiological functions from feeding to emotional behavior …
Stretchable device for simultaneous measurements of contractility and electrophysiology of neuromuscular tissue in the gastrointestinal tract
Devices interfacing with biological tissues can provide valuable insights into function,
disease, and metabolism through electrical and mechanical signals. However, certain …
disease, and metabolism through electrical and mechanical signals. However, certain …
Orally Ingested Self‐Powered Stimulators for Targeted Gut–Brain Axis Electrostimulation to Treat Obesity and Metabolic Disorders
CH Mac, HM Tai, SM Huang, HH Peng… - Advanced …, 2024 - Wiley Online Library
Obesity is a significant health concern that often leads to metabolic dysfunction and chronic
diseases. This study introduces a novel approach to combat obesity using orally ingested …
diseases. This study introduces a novel approach to combat obesity using orally ingested …
Neural signalling of gut mechanosensation in ingestive and digestive processes
Eating and drinking generate sequential mechanosensory signals along the digestive tract.
These signals are communicated to the brain for the timely initiation and regulation of …
These signals are communicated to the brain for the timely initiation and regulation of …
An ingestible, battery-free, tissue-adhering robotic interface for non-invasive and chronic electrostimulation of the gut
Ingestible electronics have the capacity to transform our ability to effectively diagnose and
potentially treat a broad set of conditions. Current applications could be significantly …
potentially treat a broad set of conditions. Current applications could be significantly …
Ingestible transiently anchoring electronics for microstimulation and conductive signaling
Ingestible electronic devices enable noninvasive evaluation and diagnosis of pathologies in
the gastrointestinal (GI) tract but generally cannot therapeutically interact with the tissue wall …
the gastrointestinal (GI) tract but generally cannot therapeutically interact with the tissue wall …
Both high fat and high carbohydrate diets impair vagus nerve signaling of satiety
H Loper, M Leinen, L Bassoff, J Sample… - Scientific Reports, 2021 - nature.com
Obesity remains prevalent in the US. One potential treatment is vagus nerve stimulation
(VNS), which activates the sensory afferents innervating the stomach that convey stomach …
(VNS), which activates the sensory afferents innervating the stomach that convey stomach …