Introduction: Statin monotherapy is generally well tolerated, with a low frequency of adverse
events. The most important adverse effects associated with statins are myopathy and an …

Statin monotherapy is generally well tolerated, with a low frequency of adverse events. The
most important adverse effects associated with statins are myopathy and an asymptomatic …

Introduction: Statins reduce the risk of cardiovascular morbidity and mortality in patients with
or at risk for cardiovascular disease and their use is expanding, especially in elderly. Statins …

Statins are one of the most well-studied class of drugs and the benefits of statins in the
treatment and prevention of both cardiovascular and cerebrovascular disease are well …

Background: As the clinical complexity of patients at high cardiovascular risk and with
multiple comorbid conditions increases, so does the potential for drug–drug interactions …

The statins are widely used worldwide to reduce risk for cardiovascular events in both the
primary and secondary prevention settings. Although generally quite safe, the statins can be …

Objective To describe the most important potential adverse effects related to statin therapy,
discuss mechanisms of toxicity and drug interactions, and suggest approaches for …

A n D GUID eLIneS affordability may often dictate which medications may be prescribed.
Patients who have exhausted prescription drug coverage or who are uninsured may require …

The 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors (statins) are
effective in reducing the risk of coronary events, and are generally very well tolerated …

While the proportion of patients with significant statin-associated adverse effects or
intolerance is very low, the increasing use and broadening indications have led to a …