HMG-CoA reductase inhibitors (statins) are the mainstay in the pharmacologic management
of dyslipidemia. Since they are widely prescribed, their safety remains an issue of concern …

This article from the National Lipid Association Statin Intolerance Panel provides a
framework for understanding statin intolerance and makes general recommendations for …

The National Lipid Association's (NLA) Statin Safety Task Force charged the Neurology
Expert Panel with the task of reviewing the scientific evidence related to adverse effects with …

Introduction: Statin intolerance is largely defined by muscle related symptoms, leading to
intolerability and cessation. The nocebo effect coupled with the challenges of diagnosing …

The beneficial effects of statins are assumed to result from their ability to reduce cholesterol
biosynthesis. However, because mevalonic acid is the precursor not only of cholesterol, but …

Meta-analyses of randomized trials of statin therapy have shown that low-ering low-density
lipoprotein cholesterol levels reduces the risk of occlusive vascular events and improves …

Background: As use of a drug becomes widespread, the full spectrum of its effects becomes
clearer. Although a link has been suggested between low or lowered cholesterol and …