Previous studies have demonstrated that bispecific hybrid antibodies produced by cell-cell
fusion or chemically conjugated heteroaggregates can direct cytotoxic T lymphocytes to kill …

The specificity and efficiency of tumor cell lysis by the retargeting of murine and human
cytolytic T lymphocytes (CTL) with heteroaggregated (also known as bispecific or hybrid) …

Cytotoxic cells express specific receptors on their sur-faces by which they distinguish altered
or foreign cells from normal autologous cells. These receptors form multiple links to …

Linking an antitumor cell antibody with an antilymphocyte antibody produces a bifunctional
antibody that can redirect T lymphocytes to lyse tumor cells. Bifunctional antibodies that …

The specificity and efficiency of tumor‐cell lysis by the retargeting of murine cytolytic
lymphocytes (CTL) with bispecific antibodies was examined. Bispecific antibodies (also …

In order to develop a rat model that reflects human weakly or nonimmunogenic tumor-host
relationships and allows investigation of T-cell retargeting with bispecific monoclonal …

Cellular cytotoxicity is mediated by receptors on the surfaces of cytotoxic cells (lysis
promoting receptors) which are specific for cell surface components on target cells. Such …

Previous studies have shown that heteroconjugates of monoclonal antibodies in which one
of the component antibodies is directed at the T-cell receptor and the other is directed …

We have previously described the generation of bispecific anti-TCR* anti-tumor mAb,
intended for in vivo analysis of T cell retargeting in a syngeneic rat colon carcinoma model …

Antibodies to the clonally unique variable-region determinants (idiotype) of the antigen-
specific alpha beta heterodimeric receptor of a clone of cytotoxic T cells (CTLs) were shown …