Targeting cancer stem cells by curcumin and clinical applications

Y Li, T Zhang - Cancer letters, 2014 - Elsevier
Curcumin is a well-known dietary polyphenol derived from the rhizomes of turmeric, an
Indian spice. The anticancer effect of curcumin has been demonstrated in many cell and …

Curcumin and cancer stem cells: curcumin has asymmetrical effects on cancer and normal stem cells

PP Sordillo, L Helson - Anticancer Research, 2015 - ar.iiarjournals.org
Curcumin has been shown to have numerous cytotoxic effects on cancer stem cells (CSCs).
This is due to its suppression of the release of cytokines, particularly interleukin (IL)-6, IL-8 …

Curcumin: a promising agent targeting cancer stem cells

S Zang, T Liu, J Shi, L Qiao - Anti-Cancer Agents in Medicinal …, 2014 - ingentaconnect.com
Cancer stem cells are a subset of cells that are responsible for cancer initiation and relapse.
They are generally resistant to the current anticancer agents. Successful anticancer therapy …

Molecular targets of curcumin for cancer therapy: an updated review

PD Kasi, R Tamilselvam, K Skalicka-Woźniak… - Tumor Biology, 2016 - Springer
In recent years, natural edible products have been found to be important therapeutic agents
for the treatment of chronic human diseases including cancer, cardiovascular disease, and …

Targeting colorectal cancer stem cells using curcumin and curcumin analogues: insights into the mechanism of the therapeutic efficacy

TS Ramasamy, AZ Ayob, HHL Myint… - Cancer cell …, 2015 - Springer
Colorectal cancer is one of the commonest cancers in the world and it is also a common
cause of cancer-related death worldwide. Despite advanced treatment strategies, the …

Curcumin mediates anticancer effects by modulating multiple cell signaling pathways

AB Kunnumakkara, D Bordoloi, C Harsha… - Clinical …, 2017 - portlandpress.com
Curcumin, a component of a spice native to India, was first isolated in 1815 by Vogel and
Pelletier from the rhizomes of Curcuma longa (turmeric) and, subsequently, the chemical …

[HTML][HTML] Anticancer effect of curcumin on breast cancer and stem cells

HT Liu, YS Ho - Food science and human wellness, 2018 - Elsevier
Numerous studies have shown that curcumin, a natural compound, exerts anticancer effects
by inhibiting cancer cell proliferation and metastasis and by inducing cell cycle arrest and …

Curcumin and cancer cells: how many ways can curry kill tumor cells selectively?

J Ravindran, S Prasad, BB Aggarwal - The AAPS journal, 2009 - Springer
Cancer is a hyperproliferative disorder that is usually treated by chemotherapeutic agents
that are toxic not only to tumor cells but also to normal cells, so these agents produce major …

The multifaceted role of curcumin in cancer prevention and treatment

MK Shanmugam, G Rane, MM Kanchi, F Arfuso… - Molecules, 2015 - mdpi.com
Despite significant advances in treatment modalities over the last decade, neither the
incidence of the disease nor the mortality due to cancer has altered in the last thirty years …

New insights into therapeutic activity and anticancer properties of curcumin

AK Panda, D Chakraborty, I Sarkar… - Journal of experimental …, 2017 - Taylor & Francis
Natural compounds obtained from plants are capable of garnering considerable attention
from the scientific community, primarily due to their ability to check and prevent the onset …