Severe acute pancreatitis causes a high incidence of mortality due to the systemic
inflammatory response syndrome leading to multiple organ failure. At present, there is no …

Acute pancreatitis is an inflammation initially localized in the pancreatic gland which may
lead to local and systemic complications. The development of severe acute pancreatitis is …

Significance: Oxidative stress plays an important role in the pathogenesis of both acute and
chronic pancreatitis. Although its impact is well investigated and has been studied clinically …

Acute pancreatitis (AP) is a severe disease with a high prevalence and 3 to 15% mortality
worldwide, which can represent an important challenge for the physician. Oxidative stress …

Oxidative stress has been implicated in the pathogenesis of acute pancreatitis, a severe and
debilitating inflammation of the pancreas that carries a significant mortality, and which …

Abstract Development of acute pancreatitis illustrates the need to understand the basic
mechanisms of disease progression to drive the exploration of therapeutic options …

Acute pancreatitis is an acute inflammatory process localized in the pancreatic gland that
frequently involves peripancreatic tissues. It is still under investigation why an episode of …

Cytokines have been shown to play a pivotal role in multiple organ dysfunction, a major
cause of death in severe acute pancreatitis. Moreover, the two-hit hypothesis of the cytokine …

Reactive oxygen species are considered mediators of the inflammatory response and tissue
damage in acute pancreatitis. We previously found that the combined treatment with …

During the last 10 years, the role of oxidative stress in pancreatitis and the benefits or
otherwise of antioxidants has been the subject of numerous research papers. There is …