Circular RNAs in osteoarthritis: indispensable regulators and novel strategies in clinical implications

W Zhang, L Qi, R Chen, J He, Z Liu, W Wang… - Arthritis Research & …, 2021 - Springer
Over the past decades, circular RNAs (circRNAs) have emerged as a hot spot and sparked
intensive interest. Initially considered as the transcriptional noises, further studies have …

[HTML][HTML] Circular RNA in osteoarthritis: an updated insight into the pathophysiology and therapeutics

D Liu, YH Liang, YT Yang, M He, ZJ Cai… - American Journal of …, 2021 - ncbi.nlm.nih.gov
Osteoarthritis (OA) is a common joint disease that mainly results in chronic pain, stiffness
and dysfunction in elderly individuals. The molecular mechanisms in the pathogenesis of OA …

Regulatory mechanism of circular RNA involvement in osteoarthritis

Y Zhang, L Liu, K Liu, M Wang, X Su, J Wang - Frontiers in Surgery, 2023 - frontiersin.org
Osteoarthritis (OA) causes joint pain, stiffness, and dysfunction in middle-aged and older
adults; however, its pathogenesis remains unclear. Circular RNAs (circRNAs) are …

Biological roles and therapeutic potential of circular RNAs in osteoarthritis

X Mao, Y Cao, Z Guo, L Wang, C Xiang - Molecular Therapy-Nucleic Acids, 2021 - cell.com
Osteoarthritis (OA) is a common and disabling joint disorder that is mainly characterized by
cartilage degeneration and narrow joint spaces. The regulatory functions of non-coding …

The potential roles of circRNAs in osteoarthritis: a coming journey to find a treasure

HZ Li, Z Lin, XH Xu, N Lin, HD Lu - Bioscience reports, 2018 - portlandpress.com
Osteoarthritis (OA), a common joint disease in elderly, causes serious social and economic
burdens worldwide. Previous studies indicated that some differentially expressed circular …

Current status of functional studies on circular RNAs in rheumatoid arthritis and their potential role as diagnostic biomarkers

Y Xu, F Chen - Journal of Inflammation Research, 2021 - Taylor & Francis
Circular RNAs (circRNAs), a new class of endogenous non-coding RNAs (ncRNAs), are
highly stable and exhibit tissue-specific expression. Accumulating evidence has indicated …

[HTML][HTML] Implications and theragnostic potentials of circular RNAs in rheumatic diseases

AA Abbas, HA Abdulkader, R Giordo… - International Journal of …, 2023 - Elsevier
Circular RNAs (circRNAs), a class of non-coding RNAs (ncRNAs), are highly stable and
ubiquitous molecules that exhibit tissue-specific expression. Accumulating evidence has …

Newly discovered circRNAs in rheumatoid arthritis, with special emphasis on functional roles in inflammatory immunity

Z Li, J Wang, Y Lin, J Fang, K Xie, Z Guan… - Frontiers in …, 2022 - frontiersin.org
Circular RNA (circRNA) is a unique type of endogenous RNA. It does not have free 3′ or
5′ ends, but forms covalently closed continuous rings. Rheumatoid arthritis (RA) is a …

CircRNA-mediated ceRNA mechanism in Osteoarthritis: Special emphasis on circRNAs in exosomes and the crosstalk of circRNAs and RNA methylation

Q Xue, Y Huang, J Chang, C Cheng, Y Wang… - Biochemical …, 2023 - Elsevier
Osteoarthritis (OA) is an age-related joint disease with chronic inflammation, progressive
articular cartilage destruction and subchondral bone sclerosis. CircRNAs (circRNAs) are a …

RNA sequencing reveals the circular RNA expression profiles of osteoarthritic synovium

S Xiang, Z Li, Y Bian, X Weng - Journal of Cellular Biochemistry, 2019 - Wiley Online Library
The role of circular RNAs (circRNAs) in regulating cartilage homeostasis in osteoarthritis
(OA) has been reported. However, the regulatory mechanisms of circRNAs in OA synovium …