Strain Wars: Competitive interactions between SARS-CoV-2 strains are explained by Gibbs energy of antigen-receptor binding

M Popovic, M Popovic - Microbial risk analysis, 2022 - Elsevier
Since the beginning of the COVID-19 pandemic, SARS-CoV-2 has mutated several times
into new strains, with an increased infectivity. Infectivity of SARS-CoV-2 strains depends on …

Strain wars 3: Differences in infectivity and pathogenicity between Delta and Omicron strains of SARS-CoV-2 can be explained by thermodynamic and kinetic …

M Popovic - Microbial risk analysis, 2022 - Elsevier
In this paper, for the first time, empirical formulas have been reported of the Delta and
Omicron strains of SARS-CoV-2. The empirical formula of the Delta strain entire virion was …

[HTML][HTML] Strain wars 2: Binding constants, enthalpies, entropies, Gibbs energies and rates of binding of SARS-CoV-2 variants

M Popovic - Virology, 2022 - Elsevier
SARS-CoV-2 virus is the cause of COVID-19 pandemic and belongs to RNA viruses,
showing great tendency to mutate. Several dozens of mutations have been observed on the …

Strain Wars 5: Gibbs energies of binding of BA. 1 through BA. 4 variants of SARS-CoV-2

M Popovic - Microbial risk analysis, 2022 - Elsevier
This paper reports, for the first time, standard Gibbs energies of binding of the BA. 1, BA. 2,
BA. 3, BA. 2.13, BA. 2.12. 1 and BA. 4 Omicron variants of SARS-CoV-2, to the Human ACE2 …

The wind of change: Gibbs energy of binding and infectivity evolution of Omicron BA. 2.86 Pirola, EG. 5.1, XBB. 1.16 Arcturus, CH. 1.1 and BN. 1 variants of SARS-CoV …

ME Popović, G Šekularac, M Popović - Microbial Risk Analysis, 2024 - Elsevier
A question is often asked about what tomorrow brings. During the last 4 years of the COVID-
19 pandemic, this question was asked with every appearance of a new SARS-CoV-2 …

[HTML][HTML] Binding affinity and mechanisms of SARS-CoV-2 variants

Y Han, Z Wang, Z Wei, I Schapiro, J Li - Computational and structural …, 2021 - Elsevier
During the rapid worldwide spread of SARS-CoV-2, the viral genome has been undergoing
numerous mutations, especially in the spike (S) glycoprotein gene that encode a type-I …

Never ending story? Evolution of SARS-CoV-2 monitored through Gibbs energies of biosynthesis and antigen-receptor binding of Omicron BQ. 1, BQ. 1.1, XBB and …

M Popovic - Microbial risk analysis, 2023 - Elsevier
RNA viruses exhibit a great tendency to mutate. Mutations occur in the parts of the genome
that encode the spike glycoprotein and less often in the rest of the genome. This is why …

Accurate evaluation on the interactions of SARS-CoV-2 with its receptor ACE2 and antibodies CR3022/CB6

H Ding, Y Yin, Y Sheng, Y Ma - Chinese Physics Letters, 2021 - iopscience.iop.org
The spread of the coronavirus disease 2019 (COVID-19) caused by severe acute respiratory
syndrome coronavirus-2 (SARS-CoV-2) has become a global health crisis. The binding …

Omicron BA. 2.75 subvariant of SARS-CoV-2 is expected to have the greatest infectivity compared with the competing BA. 2 and BA. 5, due to most negative Gibbs …

M Popovic - BioTech, 2022 - mdpi.com
Omicron BA. 2.75 may become the next globally dominant strain of COVID-19 in 2022. The
BA. 2.75 sub-variant has acquired more mutations (9) in spike protein and other genes of …

Comparing the binding interactions in the receptor binding domains of SARS-CoV-2 and SARS-CoV

M Amin, MK Sorour, A Kasry - The journal of physical chemistry …, 2020 - ACS Publications
SARS-CoV-2, since emerging in Wuhan, China, has been a major concern because of its
high infection rate and has left more than six million infected people around the world. Many …