Computational modeling of cardiac cellular electrophysiology has a long history, and many
models are now available for different species, cell types, and experimental preparations …

The modelling of the electrophysiology of cardiac cells is one of the most mature areas of
systems biology. This extended concentration of research effort brings with it new …

The use of mathematical models to study cardiac electrophysiology has a long history, and
numerous cellular scale models are now available, covering a range of species and cell …

The traditional cardiac model-building paradigm involves constructing a composite model
using data collected from many cells. Equations are derived for each relevant cellular …

We present a review of the cardiac ventricular cell electrophysiology models developed by
Prof. Denis Noble and colleagues as an example of how models may be published using a …

Effective reuse of a quantitative mathematical model requires not just access to curated
versions of the model equations, but also an understanding of the functional capabilities of …

Models of cardiac tissue electrophysiology are an important component of the Cardiac
Physiome Project, which is an international effort to build biophysically based multi-scale …

Mathematical modeling is a powerful tool to study the complex and orchestrated biological
process of cardiac electrical activity. By integrating experimental data from key components …

Cardiac arrhythmias are a major cause of death and disability. A large number of
experimental cell and animal models have been developed to study arrhythmogenic …

Computational modelling, combined with experimental investigations, is a powerful method
for investigating complex cardiac electrophysiological behaviour. The use of rabbit-specific …