Secreted frizzled-related protein (SFRP) 2, an identified member of the SFRPs family of
molecules, is often methylated in human cancers and its down-regulation is closely related …

Secreted frizzled-related protein 1 (SFRP1) is a gene that belongs to the secreted
glycoprotein SFRP family. SFRP1 has been classified as a tumor suppressor gene due to …

The Wnt signaling pathway is implicated in a variety of biological processes ranging from
developmental cell fate to human disease. The components involved in Wnt signaling have …

The Wnt signaling system is a critical pathway that regulates embryonic development and
adult homeostasis. Secreted frizzled-related proteins (SFRPs) are extracellular inhibitors of …

The Wnt (wingless-type) signaling pathway plays an important role in embryonic
development, tissue homeostasis, and tumor progression becaluse of its effect on cell …

Background Wnt signaling is important in development and can also contribute to the
initiation and progression of cancer. The Secreted Frizzled Related Proteins (SFRPs) …

Wnt signaling is believed to be an important contributor to tumor development and has been
reported to be modulated by secreted frizzled-related proteins (SFRP). Nevertheless, the …

Secreted frizzled-related proteins (SFRPs), containing five family members (SFRPs 1–5) are
putative extracellular Wnt inhibitors. Given their abilities to inhibit Wnt signalling, as well as …

The expression and levels of secreted frizzled-related proteins (sFRPs), important Wnt
signalling antagonists, have been reported to be reduced in various cancers, and are …

The role of epigenetic inactivation of secreted frizzled‑related protein 2 (SFRP2) and its
functions in the development of oral squamous cell carcinoma (OSCC) remain to be …