Introduction Chronic inflammation causes articular bone and cartilage degeneration in
people with rheumatoid arthritis (RA). Despite recent advancements in the management of …

Abstract Objective Mesenchymal stem cells (MSCs) are precursors of tissue of mesenchymal
origin, but they also have the capacity to regulate the immune response by suppressing T …

Background Despite recent advances in the treatment of arthritis with the development of
disease-modifying antirheumatic drugs, 30% of patients still fail to respond to treatment …

Introduction Mesenchymal stem cells (MSC) therapy is a new approach to treat RA. Studies
evaluating anti-inflammatory effects of MSCs per RA severity are scarce. Our primary …

Methods We used the murine C3H10T1/2 cell line (C3 MSCs) and we derived cell clones
stably expressing vIL10 (C3-IL10 MSCs). Secretion of IL-10 was measured in cell culture …

Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune arthropathy characterized
by synovial hyperplasia leading to functional impairment. Although the exact cause of RA is …

Background Rheumatoid arthritis (RA) is a chronic and nonspecific autoimmune disease,
which leads to joint destruction and deformity. To investigate the potential of human …

Rheumatoid arthritis (RA) is an autoimmune disease that causes damage to joints. This
review focuses on the possibility of influencing the disease through immunomodulation by …

Objective The objective of this study was to investigate the efficacy of mesenchymal stem
cell (MSC) in the treatment of arthritis. Methods Mesenchymal stem cells were injected …

Mesenchymal stem cells (MSCs) have immune modulatory properties. We investigated the
potential therapeutic effects of human bone marrow (BM)-, adipose tissue (AD)-, and cord …