During cancer progression and treatment, multiple subclonal populations of tumour cells
compete with one another, with selective pressures leading to the emergence of …

Tissue biopsy is the standard diagnostic procedure for cancer. Biopsy may also provide
material for genotyping, which can assist in the diagnosis and selection of targeted therapies …

Liquid biopsy is based on minimally invasive blood tests and has a high potential to
significantly change the therapeutic strategy in cancer patients, providing an extremely …

Historically, studies of disseminated tumour cells in bone marrow and circulating tumour
cells in peripheral blood have provided crucial insights into cancer biology and the …

Examination of tumor molecular characteristics by liquid biopsy is likely to greatly influence
personalized cancer patient management. Analysis of circulating tumor DNA (ctDNA) …

Cell-free DNA fragments are shed into the bloodstream by tumor cells. The analysis of
circulating tumor DNA (ctDNA), commonly known as liquid biopsy, can be exploited for a …

Improvements in genomic and molecular methods are expanding the range of potential
applications for circulating tumour DNA (ctDNA), both in a research setting and as a'liquid …

Over the past 10 years, circulating tumor cells (CTC) and circulating tumor DNA (ctDNA)
have received enormous attention as new biomarkers and subjects of translational research …

A potential non-invasive technique for identifying and tracking cancer is a liquid biopsy. This
review article provides a comprehensive overview of the principles, applications, and …

Precision medicine refers to the choosing of targeted therapies based on genetic data. Due
to the increasing availability of data from large-scale tumor genome sequencing projects …