[HTML][HTML] Emerging role of mesenchymal stromal cells (MSCs)-derived exosome in neurodegeneration-associated conditions: a groundbreaking cell-free approach

H Yari, MV Mikhailova, M Mardasi… - Stem cell research & …, 2022 - Springer
Accumulating proofs signify that pleiotropic effects of mesenchymal stromal cells (MSCs) are
not allied to their differentiation competencies but rather are mediated mainly by the …

[HTML][HTML] Promising opportunities for treating neurodegenerative diseases with mesenchymal stem cell-derived exosomes

R Guy, D Offen - Biomolecules, 2020 - mdpi.com
Neurodegenerative disease refers to any pathological condition in which there is a
progressive decline in neuronal function resulting from brain atrophy. Despite the immense …

[PDF][PDF] Mesenchymal cell-derived exosomes as novel useful candidates for drug delivery

M Einabadi, J Ai, M Kargar, F Kafilzadeh… - Archives of …, 2020 - brieflands.com
: Mesenchymal stem cells (MSCs) are one of the most accessible adult multipotent stem
cells that can be harvested from various tissues. The tissue regeneration field uses MSCs …

The therapeutic potential of mesenchymal stem cell–derived exosomes in treatment of neurodegenerative diseases

AM Gorabi, N Kiaie, GE Barreto, MI Read, HA Tafti… - Molecular …, 2019 - Springer
Neurologic complications are commonly regarded as irreversible impairments that stem from
limited potential of regeneration of the central nervous system (CNS). On the other side, the …

[HTML][HTML] Current knowledge and future perspectives on mesenchymal stem cell-derived exosomes as a new therapeutic agent

HS Joo, JH Suh, HJ Lee, ES Bang, JM Lee - International journal of …, 2020 - mdpi.com
Mesenchymal stem cells (MSCs) are on the cusp of regenerative medicine due to their
differentiation capacity, favorable culture conditions, ability to be manipulated in vitro, and …

[HTML][HTML] MSCs-derived exosomes and neuroinflammation, neurogenesis and therapy of traumatic brain injury

Y Yang, Y Ye, X Su, J He, W Bai, X He - Frontiers in cellular …, 2017 - frontiersin.org
Exosomes are endosomal origin membrane-enclosed small vesicles (30–100 nm) that
contain various molecular constituents including proteins, lipids, mRNAs and microRNAs …

Therapeutic application of mesenchymal stem cells derived exosomes in neurodegenerative diseases: a focus on non-coding RNAs cargo, drug delivery potential …

M Hedayat, M Ahmadi, M Shoaran, J Rezaie - Life Sciences, 2023 - Elsevier
Despite the massive efforts advanced over recent years in emerging therapies for
neurodegenerative diseases, effective treatment for these diseases is still an urgent need …

[HTML][HTML] A paradigm shift in cell-free approach: the emerging role of MSCs-derived exosomes in regenerative medicine

S Moghadasi, M Elveny, HS Rahman… - Journal of translational …, 2021 - Springer
Recently, mesenchymal stem/stromal cells (MSCs) due to their pro-angiogenic, anti-
apoptotic, and immunoregulatory competencies along with fewer ethical issues are …

Mesenchymal stromal cells-derived exosome and the roles in the treatment of traumatic brain injury

YY Mot, EJ Moses, N Mohd Yusoff, KH Ling… - Cellular and Molecular …, 2023 - Springer
Traumatic brain injury (TBI) could result in life-long disabilities and death. Though the
mechanical insult causes primary injury, the secondary injury due to dysregulated …

[HTML][HTML] Mesenchymal stem cell derived-exosomes: a modern approach in translational medicine

S Nikfarjam, J Rezaie, NM Zolbanin, R Jafari - Journal of translational …, 2020 - Springer
Mesenchymal stem cells (MSCs) have captured great attention in regenerative medicine for
over a few decades by virtue of their differentiation capacity, potent immunomodulatory …