[HTML][HTML] PD-L1 immunohistochemical assays for assessment of therapeutic strategies involving immune checkpoint inhibitors in non-small cell lung cancer: a …

H Kim, HJ Kwon, SY Park, E Park, JH Chung - Oncotarget, 2017 - ncbi.nlm.nih.gov
Although immune checkpoints inhibitors have exhibited promising activity in clinical trials in
non-small cell lung cancer (NSCLC) patients, the current programmed cell death-ligand 1 …

Predictive biomarkers for response to immune checkpoint inhibitors in lung cancer: PD-L1 and beyond

H Uruga, M Mino-Kenudson - Virchows Archiv, 2021 - Springer
Immune checkpoint inhibitor (ICI) therapies, including the programmed cell death protein 1
(PD-1) axis blockade, are considered a major oncological breakthrough of the early twenty …

PD-L1 expression testing in non-small cell lung cancer

C Teixidó, N Vilariño, R Reyes… - … Advances in Medical …, 2018 - journals.sagepub.com
In recent years, immunotherapy has revolutionized and changed the standard of care in
patients with advanced non-small cell lung cancer (NSCLC). Immune checkpoint inhibitors …

PD-L1 testing using the clone 22C3 pharmDx kit for selection of patients with non–small cell lung cancer to receive immune checkpoint inhibitor therapy: are cytology …

VF Torous, D Rangachari, BP Gallant, M Shea… - Journal of the American …, 2018 - Elsevier
Introduction Programmed death ligand 1 (PD-L1) testing of non–small cell lung cancer
(NSCLC) specimens helps select patients most likely to respond to immune checkpoint …

[HTML][HTML] Use of programmed cell death protein ligand 1 assay to predict the outcomes of non-small cell lung cancer patients treated with immune checkpoint inhibitors

C Tibaldi, A Lunghi, E Baldini - World Journal of Clinical Oncology, 2017 - ncbi.nlm.nih.gov
The recent discovery of immune checkpoints inhibitors, especially anti-programmed cell
death protein 1 (PD-1) and anti-programmed cell death protein ligand 1 (PD-L1) monoclonal …

Predictive biomarkers of response to PD-1/PD-L1 immune checkpoint inhibitors in non–small cell lung cancer

K Shien, VA Papadimitrakopoulou, II Wistuba - Lung Cancer, 2016 - Elsevier
Inhibitors of the programmed cell death 1 (PD-1) pathway show the potential to substantially
increase the efficacy of therapy for various malignancies, including non–small cell lung …

Predictive potential and need for standardization of PD-L1 immunohistochemistry

S Savic Prince, L Bubendorf - Virchows Archiv, 2019 - Springer
Checkpoint inhibitors targeting the PD-1/PD-L1 axis are a promising treatment option in
several tumor types. PD-L1 expression detected by immunohistochemistry is the first …

Biomarkers for immune checkpoint inhibition in non–small cell lung cancer (NSCLC)

JN Bodor, Y Boumber, H Borghaei - Cancer, 2020 - Wiley Online Library
The emergence of immunotherapy has dramatically changed how non–small cell lung
cancer is treated, and longer survival is now possible for some patients, even those with …

[HTML][HTML] Precision medicine in immune checkpoint blockade therapy for non-small cell lung cancer

X Liu, WC Cho - Clinical and translational medicine, 2017 - Springer
Immune checkpoint blockade therapy by targeting the programmed death protein
1/programmed death ligand 1 (PD-L1) axis using antibodies has yielded promising clinical …

Immune checkpoint modulation for non–small cell lung cancer

JC Soria, A Marabelle, JR Brahmer, S Gettinger - Clinical cancer research, 2015 - AACR
Therapies targeting immune checkpoints have recently shown encouraging activity in
patients with heavily pretreated advanced non–small cell lung cancer (NSCLC) …